技术外包服务:

★角质蛋白α抗体费用 分子生物学：质粒抽提、PCR、Q-PCR、RT-PCR、分子生物学：基因合成、引物合成、基因测序、载体构建等

★蛋白工程：原核、哺乳动物蛋白表达系统等

★病毒包装：腺病毒、慢病毒等

★抗体工程：磁珠分选、病理染色、WB、ELISA、IP、IF、IHC、FACS、Confocal等等

★细胞工程：细胞表型分析(凋亡、增殖、周期、迁移、侵袭、修复、克隆形成)、细胞培养、细胞膜制备、稳定细胞株构建、细胞RNAi技术等等。

实验流程：

角质蛋白α抗体费用 英文名称  Anti-SPRR1a/Cornifin A

中文名称  角质蛋白α抗体费用 

别    名 19 kDa pancornulin; Cornifin A; Cornifin alpha; CornifinA; Small proline rich protein 1A; Small proline rich protein IA; spr; SPR IA; SPRK; SPRR 1a; SPRR1A protein; SPR1A_HUMAN.

产品属性：

浓    度  1mg/1ml

规 格  0.2ml/200μg

抗体来源  Rabbit

克隆类型   polyclonal

交叉反应   Human, Mouse, Rat, Dog

产品类型   一抗  

研究领域    免疫学 神经生物学

蛋白分子量  predicted molecular weight: 10kDa 

性    状   Lyophilized or Liquid

免 疫 原  KLH conjugated synthetic peptide derived from human SPRR1a/Cornifin A

亚    型  IgG

纯化方法   affinity purified by Protein A

储 存 液   Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

角质蛋白α抗体费用 产品应用   WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500

（石蜡切片需做抗原修复） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品介绍 The small proline rich protein (SPRR) gene family encodes a conserved group of cornified envelope (CE) proteins that are part of the human epidermal differentiation complex (EDC). The formation of the cornified envelope during the late stages of epidermal differentiation is essential for epidermal barrier function and protects the body against environmental attack and water loss. Additionally, the expression of SPRR proteins is linked to keratinocyte terminal differentiation. The SPRR gene family, namely comprises three subclasses of genes, SPRR1 (which contains two members), SPRR2 (which contains eight members) and SPRR3 (which contains one member). SPRR1 is found predominantly in follicular epidermis and oral mucosa, SPRR2 is expressed coherently in follicular and interfollicular epidermis and SPRR3 is absent in epidermis and strongly expressed in internal squamous.

Function : The ability of neurons to regenerate an axon after injury is determined by both the surrounding environment and factors intrinsic to the damaged neuron. Neuronal SPRR1A is likely a significant contributor to successful nerve regeneration. The small proline-rich repeat protein 1A (SPRR1A) is not detectable in uninjured neurons but is induced by >60-fold after peripheral axonal damage being localized to injured neurons and axons. SPRR1A is one of a group of epithelial differentiation genes, including s100c and p21/waf, that are cocurrently induced in neurons by axotomy. Overexpressed SPRR1A colocalizes with F-actin in membrane ruffles and augments axonal outgrowth on a range of substrates. In axotomized sensory neurons, reduction of SPRR1A function restricts axonal outgrowth.

Subcellular Location : Cytoplasmic

Similarity : Belongs to the cornifin (SPRR) family.

Database links : UniProtKB/Swiss-Prot: P35321.2

全、新、优、品、好四大特点：

角质蛋白α抗体费用 全：公司提供上万种产品，涵盖了生物试剂，elisa试剂盒，标准品，培养基，原装耗材，抗体、培养基、ATCC细胞等，基本上各种科研所需产品在我司都能找到。

新：产品更新速度较快，基本上每周都有新产品出现。

优：产品质量好，投诉比较少。

好：我公司具有优质的技术团队，产品一旦售出，实验过程中遇到困难可提供在线技术咨询。使您使用产品时没有任何的后顾之忧。

正在热销的相关产品：

革兰氏阴性菌(G-)选择性培养基250g用于革兰氏阴性菌的选择性培养

50320 可溶性淀粉 BR 500g incubation media 50320 可溶性淀粉 BR 500g

海枣曲霉 电工电子产品试用菌。 支/瓶

HB-PETAutoExpressMedium

沙氏葡萄糖琼脂培养基(含氯霉素) 250g 用于真菌的分离培养

根瘤菌培养基250g用于根瘤菌平板计数

L-EMB琼脂(伊红美蓝琼脂) 从乳糖非发酵的革兰氏阴性肠道杆菌中分离鉴别乳糖发酵的肠杆菌 500g incubation media L-EMB琼脂(伊红美蓝琼脂) 从乳糖非发酵的革兰氏阴性肠道杆菌中分离鉴别乳糖发酵的肠杆菌 500g

菲律宾链霉菌 支/瓶

RoseBengalMedium

PotatoDextroseAgar(Chloramphenicol)

MUGNutrientAgar

MCP琼脂 MCP Agar 用于产气荚膜梭菌的计数和培养

华伦斯坦实验室营养琼脂 WL Nutrient Agar 250克 啤酒和发酵产品中酵母菌和细菌的计数

肠球菌琼脂(胆盐-七叶苷-叠琼脂)250用于肠球菌和肠道致病菌的分离培养(Acumedia方法)incubationmedia肠球菌琼脂(胆盐-七叶苷-叠琼脂)250用于肠球菌和肠道致病菌的分离培养(Acumedia方法)

ManitolSaltAgar

CL-0256AM(人腺样囊性癌细胞(高转移))5×106cells/瓶×2

SCN3B Others Human 人 SCN3B 人细胞裂解液 (阳性对照)

小鼠*上皮细胞完全培养基 100mL

B16小鼠细胞 B16 mouse melanoma cells RPMI-1640(GIBCO)+10%FBS

IL33 Protein Human 重组人 IL33 / Ierleukin-33 / NF-HEV 蛋白

PC-3M-2B4(人低转移细胞株) 5×106cells/瓶×2 CHO/dhFr-(中国仓鼠二氢叶酸还原酶缺陷细胞)

角质蛋白α抗体费用CL-0253A-427(人细胞)5×106cells/瓶×2

PGF Others Mouse 小鼠 PIGF / PLGF 人细胞裂解液 (阳性对照)

人膀胱平滑肌细胞cDNAHBdSMC cDNA

SK-BR-3细胞，人癌细胞 草鱼肾细胞系,GIK细胞 肺大平滑肌细胞Many types of cells包装：5 × 105次方(1ml)

WL1(大鼠肺细胞) 5×106cells/瓶×2

NHDF Pellet 正常人皮肤成纤维细胞团块(少年者) > 1 mio.cells 硝基苯磷酸(pNPP)磷酸酶检测试剂盒pNPP