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丝氨酸/精氨酸相关核基质蛋白4抗体品牌 英文名称  Anti-SRRM4

中文名称  丝氨酸/精氨酸相关核基质蛋白4抗体品牌 

别    名 Neural-specific serine/arginine repetitive splicing factor of 100 kDa; Neural-specific SR-related protein of 100 kDa; nSR100; Serine/arginine repetitive matrix protein 4; Srrm4; SRRM4_HUMAN.

产品属性：

浓    度  1mg/1ml

规 格  0.2ml/200μg

抗体来源  Rabbit

克隆类型   polyclonal

交叉反应   Human, Mouse, Rat, Chicken, Dog, Cow, Sheep

产品类型   一抗  

研究领域    细胞生物 发育生物学 神经生物学 信号转导 细胞周期蛋白 细胞分化 表观遗传学

蛋白分子量  predicted molecular weight: 69kDa 

性    状   Lyophilized or Liquid

免 疫 原  KLH conjugated synthetic peptide derived from human SRRM4

亚    型  IgG

纯化方法   affinity purified by Protein A

储 存 液   Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

丝氨酸/精氨酸相关核基质蛋白4抗体品牌 产品应用   WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500

（石蜡切片需做抗原修复） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品介绍 Splicing factor specifically required for neural cell differentiation. Acts in conjuction with nPTB/PTBP2 by binding directly to its regulated target transcripts and promotes neural-specific exon inclusion in many genes that function in neural cell differentiation. Required to promote the inclusion of neural-specific exon 10 in nPTB/PTBP2, leading to increased expression of neural-specific nPTB/PTBP2. Also promotes the inclusion of exon 16 in DAAM1 in neuron extracts.

Function : Splicing factor specifically required for neural celldifferentiation. Acts in conjuction with nPTB/PTBP2 by bindingdirectly to its regulated target transcripts and promotesneural-specific exon inclusion in many genes that function inneural cell differentiation. Required to promote the inclusion ofneural-specific exon 10 in nPTB/PTBP2, leading to increasedexpression of neural-specific nPTB/PTBP2. Also promotes theinclusion of exon 16 in DAAM1 in neuron extracts (By similarity).

Subcellular Location : Nucleus (By similarity).

Tissue Specificity : Specifically expressed in neuronal cells (atprotein level). Expressed in the cerebellum.

Post-translational modifications : Phosphorylated (By similarity).

Similarity : Belongs to the nSR100 family.

Database links : UniProtKB/Swiss-Prot: A7MD48.2

实验流程：

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