细胞质和纺锤体机化蛋白A抗体规格 英文名称  Anti-SPECC1L

中文名称  细胞质和纺锤体机化蛋白A抗体规格 

别    名 Cytokinesis and spindle organization A; Cytospin-A; CYTSA; CYTSA_HUMAN; Renal carcinoma antigen NY-REN-22; SPECC1-like protein; specc1l; Sperm antigen with calponin homology and coiled-coil domains 1-like.

产品属性：

浓    度  1mg/1ml

规 格  0.2ml/200μg

抗体来源  Rabbit

克隆类型   polyclonal

交叉反应   Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep

产品类型   一抗  

研究领域    细胞生物 细胞周期蛋白 细胞分化

蛋白分子量  predicted molecular weight: 125kDa 

性    状   Lyophilized or Liquid

免 疫 原  KLH conjugated synthetic peptide derived from human SPECC1L

亚    型  IgG

纯化方法   affinity purified by Protein A

储 存 液   Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

细胞质和纺锤体机化蛋白A抗体规格 产品应用   WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500

（石蜡切片需做抗原修复） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品介绍 Involved in cytokinesis and spindle organization.

Function : Involved in cytokinesis and spindle organization. May play a role in actin cytoskeleton organization and microtubule stabilization and hence required for proper cell adhesion and migration.

Subunit : May interact with both microtubules and actin cytoskeleton.

Subcellular Location : Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle. Cell junction, gap junction. Note=Colocalizes with acetylated alpha-tubulin, gamma-tubulin and F-actin. Also observed in a ring around gamma-tubulin containing centrioles possibly in the microtubule organizing center.

DISEASE : Defects in SPECC1L are the cause of facial clefting oblique type 1 (OBLFC1) [MIM:600251]. A rare form of facial clefting. A facial cleft is any of the fissures between the embryonic prominences that normally unite to form the face.

Similarity : Belongs to the cytospin-A family.

Contains 1 CH (calponin-homology) domain.

Database links : UniProtKB/Swiss-Prot: Q69YQ0.2

实验流程：

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