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核转录因子SOX6抗体规格
  • 品牌:上海莼试
  • 产地:进口、国产
  • 货号:CS12246
  • 发布日期: 2019-02-20
  • 更新日期: 2024-12-27
产品详请
产地 进口、国产
品牌 上海莼试
保存条件 Store at -20 °C
货号 CS12246
应用范围 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
CAS编号
抗体名 Anti-SOX6
克隆性
靶点 详见说明书
适应物种 详见说明书
形态 详见说明书
宿主 详见说明书
亚型 IgG
标识物 详见说明书
浓度 1mg/1ml%
免疫原 KLH conjugated synthetic peptide derived from human SOX6 (1-100aa)

核转录因子SOX6抗体规格 英文名称  Anti-SOX6

中文名称  核转录因子SOX6抗体规格 

     HSSOX 6; HSSOX6; SOX-6 SOX 6; SOX6_HUMAN.

产品属性:

      1mg/1ml

  0.2ml/200μg

抗体来源  Rabbit

克隆类型   polyclonal

交叉反应   Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep

产品类型   一抗  

研究领域    神经生物学 信号转导 转录调节因子

蛋白分子量  predicted molecular weight: 92kDa 

       Lyophilized or Liquid

  KLH conjugated synthetic peptide derived from human SOX6 (1-100aa)

      IgG

纯化方法   affinity purified by Protein A

   Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

核转录因子SOX6抗体规格 产品应用   ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500

(石蜡切片需做抗原修复) 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品介绍 Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.

Function : Transcriptional activator. Binds specifically to the DNA sequence 5'-AACAAT-3'. Plays a key role in several developmental processes, including neurogenesis and skeleton formation.

Subunit : Interacts with DAZAP2

Subcellular Location : Nucleus.

Tissue Specificity : Expressed in a wide variety of tissues, most abundantly in skeletal muscle.

Post-translational modifications : Sumoylation inhibits the transcriptional activity.

Similarity : Contains 1 HMG box DNA-binding domain.

Database links : UniProtKB/Swiss-Prot: P35712.3

实验流程:

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技术外包服务:

核转录因子SOX6抗体规格 分子生物学:质粒抽提、PCRQ-PCRRT-PCR、分子生物学:基因合成、引物合成、基因测序、载体构建等

蛋白工程:原核、哺乳动物蛋白表达系统等

病毒包装:腺病毒、慢病毒等

抗体工程:磁珠分选、病理染色、WBELISAIPIFIHCFACSConfocal等等

细胞工程:细胞表型分析(凋亡、增殖、周期、迁移、侵袭、修复、克隆形成)、细胞培养、细胞膜制备、稳定细胞株构建、细胞RNAi技术等等。

 


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