丝氨酸/苏氨酸蛋白激酶2抗体说明书 英文名称  Anti-STK2

中文名称  丝氨酸/苏氨酸蛋白激酶2抗体说明书 

别    名 CTCL tumor antigen se20 9; LOSK; se20 9; Serine/threonine protein kinase 2; STK2; SLK; SNF1 sucrose nonfermenting like kinase; STE20 like serine/threonine-protein kinase; STE20 related kinase; STK2; SLK_HUMAN.

产品属性：

浓    度  1mg/1ml

规 格  0.2ml/200μg

抗体来源  Rabbit

克隆类型   polyclonal

交叉反应   Human, Mouse, Rat, Dog, Horse, Rabbit, Sheep

产品类型   一抗  

研究领域    细胞生物 神经生物学 信号转导 细胞凋亡 激酶和磷酸酶 细胞骨架

蛋白分子量  predicted molecular weight: 143kDa 

性    状   Lyophilized or Liquid

免 疫 原  KLH conjugated synthetic peptide derived from human STK2 (885-931aa)

亚    型  IgG

纯化方法   affinity purified by Protein A

储 存 液   Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

丝氨酸/苏氨酸蛋白激酶2抗体说明书 产品应用   WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500

（石蜡切片需做抗原修复） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品介绍 SLK is a member of the serine/threonine kinase subfamily, Ste20. This subfamily is comprised of several mammalian kinases which exhibit sequence similarity to the Saccharomyces cerevisiae serine/threonine kinase Ste20, a protein involved in relaying signals from G protein-coupled receptors to cytosolic MAP kinase cascades. Members of this subfamily include KHS, GLK, YSK1, HPK1, Krs-1, Krs-2, GC kinase, HGK and SLK. SLK is a ubiquitously expressed protein that localizes to the cytoplasm and contains an N-terminal protein kinase domain, a central coiled-coil domain and a C-terminal ATH domain. SLK is activated through cleavage by caspase-3. SLK indirectly associates with microtubules and plays an important role in cellular stress, cell motility, cell death and cytoskeletal dynamics.

Function : SLK is a serine/threonine protein kinase that is involved in cytoskeletal reorganization and apoptosis. SLK is a microtubule-associated protein inducing actin stress fiber disassembly, it also mediates apoptosis and it is ubiquitously expressed; highest expression is found in heart and in skeletal muscle. There are two named isoforms.

Subcellular Location : Cytoplasmic

Tissue Specificity : Ubiquitously expressed. Highest expression is found in heart and in skeletal muscle.

Post-translational modifications : Proteolytically cleaved by caspase-3.

Autophosphorylated. Phosphorylated upon DNA damage, probably by ATM or ATR.

Similarity : Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

Contains 1 protein kinase domain.

Contains 1 UVR domain.

Database links : UniProtKB/Swiss-Prot: Q9H2G2.1

实验流程：

全、新、优、品、好四大特点：

丝氨酸/苏氨酸蛋白激酶2抗体说明书 全：公司提供上万种产品，涵盖了生物试剂，elisa试剂盒，标准品，培养基，原装耗材，抗体、培养基、ATCC细胞等，基本上各种科研所需产品在我司都能找到。

新：产品更新速度较快，基本上每周都有新产品出现。

优：产品质量好，投诉比较少。

好：我公司具有优质的技术团队，产品一旦售出，实验过程中遇到困难可提供在线技术咨询。使您使用产品时没有任何的后顾之忧。

正在热销的相关产品：

运输蛋白颗粒复合体6B 多克隆抗体  TPC6B Polyclonal Antibody  700/30ul#1540/100ul#2520/200ul

蛋白D52L1 多克隆抗体  TPD53 Polyclonal Antibody  700/30ul#1540/100ul#2520/200ul

三肽基肽酶Ⅰ 多克隆抗体  TPP1 Polyclonal Antibody  700/30ul#1540/100ul#2520/200ul

运输蛋白颗粒复合体4 多克隆抗体  TPPC4 Polyclonal Antibody  700/30ul#1540/100ul#2520/200ul

促微管蛋白聚合蛋白/脑特异蛋白p25α 多克隆抗体  TPPP Polyclonal Antibody  700/30ul#1540/100ul#2520/200ul

锚定蛋白B抗体     整合素β1结合蛋白2抗体

铜转运蛋白质α链抗体     整合素αX抗体

单克隆/*抗体     整合素αV抗体

基因ras同源家族1抗体     整合素αVβ6抗体

转录激活蛋白2α/TFAP2α/AP-2α抗体     整合素αVβ5抗体

血小板源性生长因子AB+BB抗体     Mob1同源蛋白MOBKL2C抗体

多腺苷二磷酸多聚酶3抗体/多聚ADP-核糖聚合酶3     Mob1同源蛋白MOBKL2B抗体

多腺苷二磷酸多聚酶4抗体/多聚ADP-核糖聚合酶4     MMF诱导片段蛋白1抗体

肽聚糖识别蛋白1抗体     MHC I类链相关蛋白B

前细胞胀亡受体诱导膜损伤蛋白抗体     MHC I类链相关蛋白A/组织相容性复合物MHCIa抗体

白头翁 Pul-satilla chinensisRegel Pulchinenoside A 白头翁皂苷A 129724-84-1 C41H66O12 ≥98%

佛手柑内酯BqrgcptqnHPLC≥98%,20mg/支

雷公藤红素 Celasol 34157-83-0 20mg HPLC≥99% 雷公藤红素用于含量测定

中药对照药材土茯苓121439-200401TLC法鉴别

5-caffeoylinoneic Acid5-加非酰奎宁酸纯度：≥97%

丝氨酸/苏氨酸蛋白激酶2抗体说明书隐丹参酮 35825-57-1 检测用对照品 无

云南含笑Michelia yunnanensis 鹅掌揪内酯 41059-80-7 C17H22O5 ≥98% 十七种安基酸混合溶液标准物质

Araloside X辽东楤木皂苷X分子式:C60H98O28

Chlorzoxazone录唑沙宗标准品95-25-0350mg

车桑子Dodonaea viscosa Dodoviscin H (-)-5,7-二羟基-2-[4-羟基-3-(4-羟基-3-甲基丁基)-5-(3-甲基-2-丁烯-1-基)本基]-3-甲氧基-4H-1-本并-4-酮 1372527-39-3 C26H30O7 ≥95%

技术外包服务:

★丝氨酸/苏氨酸蛋白激酶2抗体说明书 分子生物学：质粒抽提、PCR、Q-PCR、RT-PCR、分子生物学：基因合成、引物合成、基因测序、载体构建等

★蛋白工程：原核、哺乳动物蛋白表达系统等

★病毒包装：腺病毒、慢病毒等

★抗体工程：磁珠分选、病理染色、WB、ELISA、IP、IF、IHC、FACS、Confocal等等

★细胞工程：细胞表型分析(凋亡、增殖、周期、迁移、侵袭、修复、克隆形成)、细胞培养、细胞膜制备、稳定细胞株构建、细胞RNAi技术等等。