产地 | 进口、国产 |
品牌 | 上海莼试 |
保存条件 | Store at -20 °C |
货号 | CS12215 |
应用范围 | WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 |
CAS编号 | |
抗体名 | Anti-SV2C |
克隆性 | 是 |
靶点 | 详见说明书 |
适应物种 | 详见说明书 |
形态 | 详见说明书 |
宿主 | 详见说明书 |
亚型 | IgG |
标识物 | 详见说明书 |
浓度 | 1mg/1ml% |
免疫原 | KLH conjugated synthetic peptide derived from human SV2C |
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突触泡蛋白2C抗体品牌 全:公司提供上万种产品,涵盖了生物试剂,elisa试剂盒,标准品,培养基,原装耗材,抗体、培养基、ATCC细胞等,基本上各种科研所需产品在我司都能找到。
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突触泡蛋白2C抗体品牌 英文名称 Anti-SV2C
中文名称 突触泡蛋白2C抗体品牌
别 名 Synaptic vesicle protein 2c; SV2C_HUMAN.
产品属性:
浓 度 1mg/1ml
规 格 0.2ml/200μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat, Pig, Rabbit
产品类型 一抗
研究领域 细胞生物 神经生物学 信号转导 通道蛋白
蛋白分子量 predicted molecular weight: 82kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human SV2C
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
突触泡蛋白2C抗体品牌 产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 In all vertebrates, SV2 proteins are abundant, hydrophobic, membrane glycoproteins that are expressed as two major isoforms, SV2A and SV2B, and one minor isoform, SV2C. SV2 proteins are differentially expressed in the brain and are present on all synaptic vesicles, independent of transmitter type. SV2A is abundantly expressed in the subcortex, specifically in the synaptic vesicles of all presynaptic nerve terminals, and also in most neuroendocrine secretory granules. SV2B displays a more restricted pattern of expression in that it is only present on a small subset of synapses in the hippocampus and cortex. SV2A and SV2B are funtionally redundant and are required for maintaining normal brain function in vertebrates. SV2A and SV2B mediate synaptic transmission by regulating cytoplasmic Ca2+ levels in the nerve terminal during repetitive stimulation.
Function : Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles (By similarity).
Subunit : Interacts with SYT1 in a calcium-dependent manner (By similarity).
Subcellular Location : Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein (By similarity). Note=Enriched in small synaptic vesicles and adrenal microsomes, not present in chromaffin granules. Associated with both insulin granules and synaptic-like microvesicles in insulin-secreting cells of the pancreas (By similarity).
Post-translational modifications : N-glycosylated (By similarity).
Similarity : Belongs to the major facilitator superfamily.
Database links : UniProtKB/Swiss-Prot: Q496J9.1
实验流程:
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★突触泡蛋白2C抗体品牌 分子生物学:质粒抽提、PCR、Q-PCR、RT-PCR、分子生物学:基因合成、引物合成、基因测序、载体构建等
★蛋白工程:原核、哺乳动物蛋白表达系统等
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