突触泡蛋白2B抗体规格 英文名称  Anti-SV2B

中文名称  突触泡蛋白2B抗体规格 

别    名 Synaptic vesicle protein 2B; SV2B_HUMAN.

产品属性：

浓    度  1mg/1ml

规 格  0.2ml/200μg

抗体来源  Rabbit

克隆类型   polyclonal

交叉反应   Human, Mouse, Rat, Chicken, Rabbit

产品类型   一抗  

研究领域    细胞生物 神经生物学

蛋白分子量  predicted molecular weight: 77kDa 

性    状   Lyophilized or Liquid

免 疫 原  KLH conjugated synthetic peptide derived from human SV2B

亚    型  IgG

纯化方法   affinity purified by Protein A

储 存 液   Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

突触泡蛋白2B抗体规格 产品应用   WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500

（石蜡切片需做抗原修复） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品介绍 In all vertebrates, SV2 proteins are abundant, hydrophobic, membrane glycoproteins that are expressed as two major isoforms, SV2A and SV2B, and one minor isoform, SV2C. SV2 proteins are differentially expressed in the brain and are present on all synaptic vesicles, independent of transmitter type. SV2A is abundantly expressed in the subcortex, specifically in the synaptic vesicles of all presynaptic nerve terminals, and also in most neuroendocrine secretory granules. SV2B displays a more restricted pattern of expression in that it is only present on a small subset of synapses in the hippocampus and cortex. SV2A and SV2B are funtionally redundant and are required for maintaining normal brain function in vertebrates. SV2A and SV2B mediate synaptic transmission by regulating cytoplasmic Ca2+ levels in the nerve terminal during repetitive stimulation.

Function : SV2s (Synaptic Vesicle protein 2) are integral membrane glycoproteins present in all synaptic vesicles. They have 12 transmembrane domains predicted by sequence analysis. There are three characterized isoforms, SV2A, SV2B and SV2C. While SV2A is expressed ubiquitously throughout the brain, SV2B has a more restricted distribution with varying degrees of coexpression with SV2A. SV2C is more closely related to SV2A but shows a very restricted expression pattern.

Subunit : Interacts with SYT1 in a calcium-independent manner. Forms a complex with SYT1, syntaxin-1 and SNAP25 (By similarity).

Subcellular Location : Cytoplasmic vesicle, secretory vesicle. Synaptic vesicle membrane; Multi-pass membrane protein.

Post-translational modifications : N-glycosylated (By similarity).

The N-terminal cytoplasmic domain is phosphorylated by CK1 (By similarity).

Similarity : Belongs to the major facilitator superfamily.

Database links : UniProtKB/Swiss-Prot: Q7L1I2.1

实验流程：

全、新、优、品、好四大特点：

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金钱松Pseudolarix kaempferi Pseudolaric acid D 土槿 D 115028-67-6 C20H30O3 ≥95%

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中药对照药材漆姑草121425-200501TLC法鉴别

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突触泡蛋白2B抗体规格山耐酚 Kaempferol 分 子 量：286.2400 CAS编号：520-18-3 分子式：C15H10O6 别　　名：莰飞醇，3,4',5,7-四羟基黄酮 【性状】为黄色针晶。熔点276℃-278℃ 山耐酚微溶于水，溶于热乙醇，以醚和碱。山耐酚属于黄酮醇类。

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肉豆蔻 Myristica fragrans Hot Myrislignan 肉豆蔻木脂素 171485-39-5 C21H26O6 ≥98%

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