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钠通道蛋白11α抗体品牌
  • 品牌:上海莼试
  • 产地:进口、国产
  • 货号:CS12179
  • 发布日期: 2019-02-18
  • 更新日期: 2024-11-27
产品详请
产地 进口、国产
品牌 上海莼试
保存条件 Store at -20 °C
货号 CS12179
应用范围 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
CAS编号
抗体名 Anti-SCN11A/NAV1.9
克隆性
靶点 详见说明书
适应物种 详见说明书
形态 详见说明书
宿主 详见说明书
亚型 IgG
标识物 详见说明书
浓度 1mg/1ml%
免疫原 KLH conjugated synthetic peptide derived from human SCN11A/NAV1.9 (656-705aa)

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钠通道蛋白11α抗体品牌 全:公司提供上万种产品,涵盖了生物试剂,elisa试剂盒,标准品,培养基,原装耗材,抗体、培养基、ATCC细胞等,基本上各种科研所需产品在我司都能找到。

新:产品更新速度较快,基本上每周都有新产品出现。

优:产品质量好,投诉比较少。

好:我公司具有优质的技术团队,产品一旦售出,实验过程中遇到困难可提供在线技术咨询。使您使用产品时没有任何的后顾之忧。

钠通道蛋白11α抗体品牌 英文名称  Anti-SCN11A/NAV1.9

中文名称  钠通道蛋白11α抗体品牌 

     hNaN; NaN; NAV1.9; Peripheral nerve sodium channel 5; PN 5; PN5; SCN 11A; SCN 12A; SCN12A; Sensory neuron sodium channel 2; SNS 2; SNS2; Sodium channel protein type 11 subunit alpha; Sodium channel protein type XI subunit alpha; Sodium channel voltage gated type XI alpha; Sodium channel voltage gated type XI alpha polypeptide; Sodium channel voltage gated type XI alpha subunit; Sodium channel voltage gated type XII alpha polypeptide; Voltage gated sodium channel Nav1.9; Voltage gated sodium channel subunit alpha Nav1.9.

产品属性:

      1mg/1ml

  0.2ml/200μg

抗体来源  Rabbit

克隆类型   polyclonal

交叉反应   Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit

产品类型   一抗  

研究领域    神经生物学 通道蛋白 细胞膜受体

蛋白分子量  predicted molecular weight: 197kDa 

       Lyophilized or Liquid

  KLH conjugated synthetic peptide derived from human SCN11A/NAV1.9 (656-705aa)

      IgG

纯化方法   affinity purified by Protein A

   Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

钠通道蛋白11α抗体品牌 产品应用   WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500

(石蜡切片需做抗原修复) 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品介绍 Voltage gated sodium channels are membrane protein complexes that play a fundamental role in generating and transmitting action potentials in neuronal cells. SCN11A (Sodium channel, voltage gated, type XI, alpha subunit) mediates the voltage dependent sodium ion permeability and conductance. It forms the pore of the sodium selective channel through which sodium ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin resistant sodium channel isoform.

Function : This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which sodium ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-resistant sodium channel isoform. Also involved, with the contribution of the receptor tyrosine kinase NTRK2, in rapid BDNF-evoked neuronal depolarization.

Subunit : he voltage-resistant sodium channel consists of an ion conducting pore forming alpha-subunit regulated by one or more auxiliary subunits SCN1B, SCN2B and SCN3B.

Subcellular Location : Membrane; Multi-pass membrane protein.

Tissue Specificity : Expressed in the dorsal root ganglia and trigeminal ganglia, olfactory bulb, hippocampus, cerebellar cortex, spinal cord, spleen, small intestine and placenta.

Similarity : Belongs to the sodium channel (TC 1.A.1.10) family. Nav1.9/SCN11A subfamily.

实验流程:

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技术外包服务:

钠通道蛋白11α抗体品牌 分子生物学:质粒抽提、PCRQ-PCRRT-PCR、分子生物学:基因合成、引物合成、基因测序、载体构建等

蛋白工程:原核、哺乳动物蛋白表达系统等

病毒包装:腺病毒、慢病毒等

抗体工程:磁珠分选、病理染色、WBELISAIPIFIHCFACSConfocal等等

细胞工程:细胞表型分析(凋亡、增殖、周期、迁移、侵袭、修复、克隆形成)、细胞培养、细胞膜制备、稳定细胞株构建、细胞RNAi技术等等。

 


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