全、新、优、品、好四大特点：

神经迁移蛋白Slit2/3抗体说明书 全：公司提供上万种产品，涵盖了生物试剂，elisa试剂盒，标准品，培养基，原装耗材，抗体、培养基、ATCC细胞等，基本上各种科研所需产品在我司都能找到。

新：产品更新速度较快，基本上每周都有新产品出现。

优：产品质量好，投诉比较少。

好：我公司具有优质的技术团队，产品一旦售出，实验过程中遇到困难可提供在线技术咨询。使您使用产品时没有任何的后顾之忧。

神经迁移蛋白Slit2/3抗体说明书 英文名称  Anti-SLIT2/Slil3

中文名称  神经迁移蛋白Slit2/3抗体说明书 

别    名 Drad-1; E030015M03Rik; E130320P19Rik; FLJ14420; Slil 3; Slil3; Slit 2; Slit homolog 2 (Drosophila); Slit homolog 2; Slit homolog 2 protein.

产品属性：

浓    度  1mg/1ml

规 格  0.1ml/100μg 0.2ml/200μg

抗体来源  Rabbit

克隆类型   polyclonal

交叉反应   Human, Mouse, Rat

产品类型   一抗  

研究领域    细胞生物 免疫学 神经生物学 结合蛋白

蛋白分子量  predicted molecular weight: 170kDa 

性    状   Lyophilized or Liquid

免 疫 原  KLH conjugated synthetic peptide derived from human Slit2 C-terminus

亚    型  IgG

纯化方法   affinity purified by Protein A

储 存 液   0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide

神经迁移蛋白Slit2/3抗体说明书 产品应用   WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500

（石蜡切片需做抗原修复） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品介绍 Slit proteins are ligands at the Roundabout (Robo) receptors and act as guidance cues in axonal migration/navigation during neural development, at the ventral midline of the neural tube. Slit1 and Slit2 are essential for midline guidance in the forebrain by acting as repulsive signals preventing inappropriate midline crossing by axons projecting from the olfactory bulb. A number of cleavage products are reported in the literature for Slit2 protiens (following alternate splicing). The C-terminal cleavage proteins are more diffusible than the larger N-terminal protein that is more tightly cell associated. Slit2 protein is expressed in fetal lung and kidney, and adult spinal cord. Weak expression in adult adrenal gland, thyroid, trachea.

Function : Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different regions. SLIT1 and SLIT2 seem to be essential for midline guidance in the forebrain by acting as repulsive signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb. In spinal chord development may play a role in guiding commissural axons once they reached the floor plate by modulating the response to netrin. In vitro, silences the attractive effect of NTN1 but not its growth-stimulatory effect and silencing requires the formation of a ROBO1-DCC complex. May be implicated in spinal chord midline post-crossing axon repulsion. In vitro, only commissural axons that crossed the midline responded to SLIT2. In the developing visual system appears to function as repellent for retinal ganglion axons by providing a repulsion that directs these axons along their appropriate paths prior to, and after passage through, the optic chiasm. In vitro, collapses and repels retinal ganglion cell growth cones. Seems to play a role in branching and arborization of CNS sensory axons, and in neuronal cell migration. In vitro, Slit homolog 2 protein N-product, but not Slit homolog 2 protein C-product, repels olfactory bulb (OB) but not dorsal root ganglia (DRG) axons, induces OB growth cones collapse and induces branching of DRG axons. Seems to be involved in regulating leukocyte migration.

Subcellular Location : Secreted. The C-terminal cleavage protein is more diffusible than the larger N-terminal protein that is more tightly cell associated.

Tissue Specificity : Fetal lung and kidney, and adult spinal cord. Weak expression in adult adrenal gland, thyroid, trachea and other tissues examined.

Similarity : Contains 1 CTCK (C-terminal cystine knot-like) domain.

Contains 7 EGF-like domains.

Contains 1 laminin G-like domain.

Contains 20 LRR (leucine-rich) repeats.

Contains 4 LRRCT domains.

Contains 4 LRRNT domains.

实验流程：

正在热销的相关产品：

GR ELISA Kit 大鼠糖皮质类固醇受体Multi-class antibodies规格： 48T

Anti-Phospho-Tuberin/TSC2 (Ser1387) 磷酸化马铃薯球蛋白(性硬化)抗体Multi-class antibodies规格： 0.1ml

Rhesus antibody Rh GDNF Receptor alpha 2 胶质细胞系源性神经营养因子受体α2抗体 规格 0.1ml

DSIP(Human delta sleep-inducing peptide) ELISA Kit 人促睡眠肽 96T

Neurokin B receptor 英文名称： 神经激肽B受体抗体 0.2ml

ADAM2 英文名称： 去整合素样金属蛋白酶2抗体 0.1ml

Anti-Phospho-Tuberin/TSC2 (Ser1387) 磷酸化马铃薯球蛋白(性硬化)抗体Multi-class antibodies规格： 0.1ml

Anti-Dectin-1/CLECSF12/RBITC 红色荧光素罗丹明标记C型凝集素结构域家族7成员A抗体IgGMulti-class antibodies规格： 0.2ml

Anti-ERK1/MAPK3/FITC 荧光素标记原活化蛋白激酶3抗体IgGMulti-class antibodies规格： 0.2ml

Rhesus antibody Rh Calcitonin 降钙素抗体 规格 0.1ml

MEK1/MAPKK1(mitogen activated protein kinase kinase 1) MEK1/MAPKK1抗体(N-端) 0.5mg

HRASLS2 英文名称： HRAS样抑制因子2抗体 0.1ml

Rhesus antibody Rh SERPIN A11 丝氨酸蛋白酶抑制剂A11抗体 规格 0.2ml

Anti-ERK1/MAPK3/FITC 荧光素标记原活化蛋白激酶3抗体IgGMulti-class antibodies规格： 0.2ml

GKRP(Human glucokinase regulatory protein) ELISA Kit 人葡萄糖激酶调节蛋白Multi-class antibodies规格： 48T

Anti-MCM2 染色体维持缺陷蛋白2抗体Multi-class antibodies规格： 0.2ml

Rhesus antibody Rh JMJD6 凋亡细胞清除受体抗体 规格 0.2ml

ANG ELISA Kit 大鼠生长素 96T

phospho-PKC Epsilon(Ser729) 英文名称： 磷酸化蛋白激酶C/p-PKC ε抗体 0.1ml

C3orf20 英文名称： 3号染色体开放阅读框20抗体 0.2ml

Anti-MCM2 染色体维持缺陷蛋白2抗体Multi-class antibodies规格： 0.2ml

STK4 Others Human 人 STK4 / MST1 杆状病毒-昆虫细胞裂解液 (阳性对照)

人脑干星形胶质细胞HA-bs

猞猁皮肤成纤维样细胞;ELS1

BALB/3T3细胞，BALB/C小鼠胚成纤维细胞 人*癌细胞,PC-2细胞 CM-M024小鼠淋巴成纤维细胞完全培养基100mL

大鼠细胞;UMR-106

CDH1 Others Human 人 Cadherin-1 / CDH1 / CD324 / E-cadherin 人细胞裂解液 (阳性对照)

CL-0367IM-9(人外周血B淋巴细胞)5×106cells/瓶×2

CD58 Others Human 人 LFA-3 / CD58 人细胞裂解液 (阳性对照)

人平滑肌细胞总RNAHPSMC NA

MDA-MB-231细胞，人癌细胞 BALB/c小鼠ES细胞,B/c-ES细胞 BPH-1, 人细胞

NCI-H1975(人) 5×106cells/瓶×2

HDMEC adult Pellet 人真皮微内皮细胞团块(成年捐献者) > 1 mio.cells 小气道上皮细胞培养基SAEpiCM-prf

神经迁移蛋白Slit2/3抗体说明书 CL-0365HuTu-80(人十二脂肠腺癌)5×106cells/瓶×2

MRPL44 Others Human 人 MRPL44 杆状病毒-昆虫细胞裂解液 (阳性对照)

人上皮细胞总RNAHPEpiC NA

绵羊肺细胞;OAR-L1 胚胎成纤维细胞，NIH/3T3细胞 NCTC1469细胞，小鼠正常肝细胞

人胚胎皮肤成纤维细胞;HES

HA Others H11N9 甲型 H11N9 (A/mallard/Alberta/294/1977) 血凝素HA1 (Hemagglutinin) 人细胞裂解液 (阳性对照)

技术外包服务:

★神经迁移蛋白Slit2/3抗体说明书 分子生物学：质粒抽提、PCR、Q-PCR、RT-PCR、分子生物学：基因合成、引物合成、基因测序、载体构建等

★蛋白工程：原核、哺乳动物蛋白表达系统等

★病毒包装：腺病毒、慢病毒等

★抗体工程：磁珠分选、病理染色、WB、ELISA、IP、IF、IHC、FACS、Confocal等等

★细胞工程：细胞表型分析(凋亡、增殖、周期、迁移、侵袭、修复、克隆形成)、细胞培养、细胞膜制备、稳定细胞株构建、细胞RNAi技术等等。