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尿苷二磷酸葡萄糖醛酸转移酶1A9品牌 英文名称  Anti-UGT1A9

中文名称  尿苷二磷酸葡萄糖醛酸转移酶1A9品牌 

别    名 GNT1; HLUGP4; LUGP4; UDP glucuronosyltransferase 1A9; UDPGT; UGT1I; UD19_HUMAN.

产品属性：

浓    度  1mg/1ml

规 格  0.2ml/200μg

抗体来源  Rabbit

克隆类型   polyclonal

交叉反应   Human, Mouse, Rat

产品类型   一抗  

研究领域     细胞生物 免疫学 信号转导

蛋白分子量  predicted molecular weight: 57kDa 

性    状   Lyophilized or Liquid

免 疫 原  KLH conjugated synthetic peptide derived from human UGT1A9

亚    型  IgG

纯化方法   affinity purified by Protein A

储 存 液   0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide

尿苷二磷酸葡萄糖醛酸转移酶1A9品牌 产品应用   WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500

（石蜡切片需做抗原修复） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品介绍 UGT1A9 is a UDP glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N termini and identical C termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. UGT1A9 is active on phenols.

Function : UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isoform has specificity for phenols.

Subcellular Location : Microsome. Endoplasmic reticulum membrane; Single-pass membrane protein (Potential).

Tissue Specificity : Liver.

Similarity : Belongs to the UDP-glycosyltransferase family.

Database links : UniProtKB/Swiss-Prot: O60656.1

实验流程：

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