全、新、优、品、好四大特点：

核凋亡因子THAP1抗体说明书 全：公司提供上万种产品，涵盖了生物试剂，elisa试剂盒，标准品，培养基，原装耗材，抗体、培养基、ATCC细胞等，基本上各种科研所需产品在我司都能找到。

新：产品更新速度较快，基本上每周都有新产品出现。

优：产品质量好，投诉比较少。

好：我公司具有优质的技术团队，产品一旦售出，实验过程中遇到困难可提供在线技术咨询。使您使用产品时没有任何的后顾之忧。

核凋亡因子THAP1抗体说明书 英文名称  Anti-THAP1

中文名称  核凋亡因子THAP1抗体说明书 

别    名 Nuclear proapoptotic factor; THAP 1; THAP domain containing apoptosis associated protein 1; THAP domain containing protein 1; THAP domain protein 1; THAP1_HUMAN.

产品属性：

浓    度  1mg/1ml

规 格  0.2ml/200μg

抗体来源  Rabbit

克隆类型   polyclonal

交叉反应   Human, Mouse, Rat, Chicken, Dog, Cow, Rabbit, Sheep

产品类型   一抗  

研究领域    细胞生物 染色质和核信号 信号转导 细胞凋亡 细胞周期蛋白

蛋白分子量  predicted molecular weight: 25kDa 

性    状   Lyophilized or Liquid

免 疫 原  KLH conjugated synthetic peptide derived from human THAP1

亚    型  IgG

纯化方法   affinity purified by Protein A

储 存 液   Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

核凋亡因子THAP1抗体说明书 产品应用   WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500

（石蜡切片需做抗原修复） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品介绍 THAP1 contains a THAP domain, a zinc-dependent DNA-binding domain. It colocalizes with the apoptosis response protein PAWR/PAR-4 in promyelocytic leukemia (PML) nuclear bodies and is a pro-apoptopic protein that potentiates both serum-withdrawal and TNF-induced apoptosis. It is a physiologic regulator of endothelial cell proliferation and cell-cycle progression, two essential processes for angiogenesis.

Function : DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes, including RRM1. Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1. May also have pro-apoptopic activity by potentiating both serum-withdrawal and TNF-induced apoptosis.

Subunit : Interacts with PAWR. Component of a THAP1/THAP3-HCFC1-OGT complex that contains, either THAP1 or THAP3, HCFC1 and OGT. Interacts with OGT. Interacts (via the HBM) with HCFC1 (via the Kelch-repeat domain); the interaction recruits HCFC1 to the RRM1 promoter.

Subcellular Location : Nucleus, nucleoplasm. Nucleus, PML body.

Tissue Specificity : Highly expressed in heart, skeletal muscle, kidney and liver. Weaker expression in brain and placenta.

DISEASE : Defects in THAP1 are the cause of dystonia type 6 (DYT6) [MIM:602629]. DYT6 is a primary torsion dystonia. Dystonia is defined by the presence of sustained involuntary muscle contractions, often leading to abnormal postures. Dystonia type 6 is characterized by onset in early adulthood, cranial or cervical involvement in about half of the cases, and frequent progression to involve multiple body regions.

Similarity : Belongs to the THAP1 family.

Contains 1 THAP-type zinc finger.

Database links : UniProtKB/Swiss-Prot: Q9NVV9.1

实验流程：

正在热销的相关产品：

Anti-phospho-P53(pSer392)/FITC 荧光素标记抗磷酸化抑制基因P53抗体IgGMulti-class antibodies规格： 0.2ml

Rabbit Anti-mouse IgG/Gold 金标记兔抗小鼠IgG(10nm/15nm)Multi-class antibodies规格： 0.5ml

纤维连结蛋白抗体 Anti-FN 0.1ml

Goat Anti-Mouse IgG/Alexa Fluor 350 Alexa Fluor 350标记的羊抗小鼠IgG 0.1ml

FNDC4 英文名称： Ⅲ型纤维连接蛋白域蛋白4抗体 0.2ml

Rhesus antibody Rh phospho-STAT5a(Tyr694) 磷酸化信号转导和转录激活因子5a抗体 规格 0.1ml

Rabbit Anti-mouse IgG/Gold 金标记兔抗小鼠IgG(10nm/15nm)Multi-class antibodies规格： 0.5ml

MIP2 (myocardial ischemic preconditioning upregulated protein 2) 巨噬细胞蛋白2抗原Multi-class antibodies规格： 0.5mg

Anti-Angiopoietin 1 生成素-1抗体Multi-class antibodies规格： 0.1ml

Rhesus antibody Rh phospho-Beta-catenin(Tyr86) 磷酸化β 连环素蛋白抗体 规格 0.1ml

包被缓冲液(PH9.6) 100ml 进口分装

VTG 英文名称： 鱼、青鳉鱼卵黄蛋白原抗体 0.2ml

DLGAP4 英文名称： PSD95结合蛋白4抗体 0.2ml

Anti-Angiopoietin 1 生成素-1抗体Multi-class antibodies规格： 0.1ml

Anti-Gastrin/FITC 荧光素标记胃泌素/蛙皮素抗体IgGMulti-class antibodies规格： 0.2ml

Anti-Phospho-NMDAR1 (Ser890)/FITC 荧光素标记磷酸化谷氨酸受体1抗体IgGMulti-class antibodies规格： 0.2ml

Rhesus antibody Rh Borealin/CDCA8 细胞分裂周期蛋白8抗体 规格 0.2ml

HSP-70 peptide 热休克蛋白-70(多肽抗原) 0.5mg

DNAJA1 英文名称： 热休克蛋白相关蛋白4抗体 0.2ml

Rhesus antibody Rh RERE 肌相关蛋白1抗体 规格 0.2ml

Anti-Phospho-NMDAR1 (Ser890)/FITC 荧光素标记磷酸化谷氨酸受体1抗体IgGMulti-class antibodies规格： 0.2ml

人β乳球蛋白(β-Lg)ELISA 试剂盒 96T/48T 试剂盒 组装/原装

兔子骨形成蛋白2(BMP2)免疫试剂盒 Rabbit Bone morphogenetic protein 2,BMP2 ELISA kit

衣原体蛋白酶样活性因子(CPAF)ELISA试剂盒 ，英文名： CPAF ELISA Kit

Porcinemacrophageinflammatoryprotein1α,MIP-1αELISA试剂盒猪巨噬细胞炎性蛋白1α(MIP-1α/CCL3)ELISA试剂盒规格：96T/48T

Humanalpha-L-fucosidase,AFUELISA试剂盒人αL岩藻糖苷酶(AFU)ELISA试剂盒规格：96T/48T

HumanAquaporin2，AQP-2ELISAKit人水通道蛋白2(AQP-2)ELISA试剂盒规格：96T/48T

大鼠瘦素(LEP)ELISA 试剂盒 96T/48T 试剂盒 组装/原装

人天门冬氨酰-NA合成酶(DARS)免疫试剂盒 Human Aspayl-NA syhetase, cytoplasmic,DARS ELISA kit

基比林-N-去甲基化酶(AND)测试盒 可见分光光度法 50管/24样

RatStemCellFactorReceptor,SCFRELISA试剂盒大鼠干细胞因子受体(SCFR)ELISA试剂盒规格：96T/48T

HumanKeratinocyteGrowthFactor,KGFELISA试剂盒人角化细胞生长因子(KGF)ELISA试剂盒规格：96T/48T

Humanneuraminidase,NAELISAKit人神经氨酸酶(NA)ELISA试剂盒规格：96T/48T

核凋亡因子THAP1抗体说明书 大鼠微管关联蛋白4(MAP4)ELISA试剂盒 ，英文名： MAP4 ELISA Kit

The cow Niu Xiaochang alkaline phosphatase (CIAP) ELISA Kit 牛的牛小肠碱性磷酸酶(CIAP)ELISA试剂盒

RatLeptinSolubleReceptor,sLRELISAKit 大鼠可溶性瘦素受体(sLR)ELISA试剂盒 96T/48T 进口分装

CLIAKitforHpt/HP(RabbitHaptoglobin)ELISAKit兔结合珠蛋白/触珠蛋白规格：48T/96T

细胞PAK4激酶活性定量检测试剂盒(A/B/C)20次

ELISAKitα-glucosidase大鼠α葡萄糖苷酶规格：48T/96T

技术外包服务:

★核凋亡因子THAP1抗体说明书 分子生物学：质粒抽提、PCR、Q-PCR、RT-PCR、分子生物学：基因合成、引物合成、基因测序、载体构建等

★蛋白工程：原核、哺乳动物蛋白表达系统等

★病毒包装：腺病毒、慢病毒等

★抗体工程：磁珠分选、病理染色、WB、ELISA、IP、IF、IHC、FACS、Confocal等等

★细胞工程：细胞表型分析(凋亡、增殖、周期、迁移、侵袭、修复、克隆形成)、细胞培养、细胞膜制备、稳定细胞株构建、细胞RNAi技术等等。