中文名称  瞬时受体电位离子通道蛋白5抗体（M亚家族）规格 

英文名称  Anti-TRPM5

别    名 MLSN1 and TRP related gene 1; MLSN1 and TRP related gene 1 protein; MLSN1 and TRP-related; MLSN1- and TRP-related gene 1 protein; MTR1; Novel protein similar to vertebrate transient receptor potential cation channel, subfamily M, member 5 ; Transient receptor potential cation channel subfamily M member 5; Transient receptor potential cation channel, subfamily M, member 5; Trpm5; TRPM5 transient receptor potential cation channel, subfamily M, member 5; TRPM5_HUMAN; 9430099A16Rik; Long transient receptor potential channel 5; LTrpC-5; LTrpC5.

产品属性：

瞬时受体电位离子通道蛋白5抗体（M亚家族）规格 浓    度  1mg/1ml

规 格  0.2ml/200μg

抗体来源  Rabbit

克隆类型   polyclonal

交叉反应   Human, Mouse, Rat, Cow

产品类型   一抗  

研究领域    细胞生物 免疫学 神经生物学

蛋白分子量  predicted molecular weight: 131kDa 

性    状   Lyophilized or Liquid

免 疫 原  KLH conjugated synthetic peptide derived from human TRPM5

亚    型  IgG

纯化方法   affinity purified by Protein A

储 存 液   Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

瞬时受体电位离子通道蛋白5抗体（M亚家族）规格 产品应用   WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200

（石蜡切片需做抗原修复） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品介绍 Voltage-modulated Ca(2+)-activated, monovalent cation channel (VCAM) that mediates a transient membrane depolarization and plays a central role in taste transduction. Monovalent-specific, non-selective cation channel that mediates the transport of Na(+), K(+) and Cs(+) ions equally well. Activated directly by increases in intracellular Ca(2+), but is impermeable to it. Gating is voltage-dependent and displays rapid activation and deactivation kinetics upon channel stimulation even during sustained elevations in Ca(2+). Also activated by a fast intracellular Ca(2+) increase in response to inositol 1,4,5-triphosphate-producing receptor agonists. The channel is blocked by extracellular acidification. External acidification has 2 effects, a fast reversible block of the current and a slower irreversible enhancement of current inactivation. Is a highly temperature-sensitive, heat activated channel showing a steep increase of inward currents at temperatures between 15 and 35 degrees Celsius. Heat activation is due to a shift of the voltage-dependent activation curve to negative potentials. Activated by arachidonic acid in vitro. May be involved in perception of bitter, sweet and umami tastes. May also be involved in sensing semiochemicals.

Function : Voltage-modulated Ca(2+)-activated, monovalent cation channel (VCAM) that mediates a transient membrane depolarization and plays a central role in taste transduction. Monovalent-specific, non-selective cation channel that mediates the transport of Na(+), K(+) and Cs(+) ions equally well. Activated directly by increases in intracellular Ca(2+), but is impermeable to it. Gating is voltage-dependent and displays rapid activation and deactivation kinetics upon channel stimulation even during sustained elevations in Ca(2+). Also activated by a fast intracellular Ca(2+) increase in response to inositol 1,4,5-triphosphate-producing receptor agonists. The channel is blocked by extracellular acidification. External acidification has 2 effects, a fast reversible block of the current and a slower irreversible enhancement of current inactivation. Is a highly temperature-sensitive, heat activated channel showing a steep increase of inward currents at temperatures between 15 and 35 degrees Celsius. Heat activation is due to a shift of the voltage-dependent activation curve to negative potentials. Activated by arachidonic acid in vitro. May be involved in perception of bitter, sweet and umami tastes. May also be involved in sensing semiochemicals.

Subcellular Location : Cell membrane

Tissue Specificity : Strongly expressed in fetal brain, liver and kidney, and in adult prostate, testis, ovary, colon and peripheral blood leukocytes. Also expressed in a large proportion of Wilms' tumors and rhabdomyosarcomas. In monochromosomal cell lines shows exclusive paternal expression.

Similarity : Belongs to the transient receptor (TC 1.A.4) family. LTrpC subfamily. TRPM5 sub-subfamily.

Database links :

Entrez Gene: 29850 Human

Entrez Gene: 56843 Mouse

Entrez Gene: 365391 Rat

Omim: 604600 Human

SwissProt: Q9NZQ8 Human

SwissProt: Q9JJH7 Mouse

Unigene: 272287 Human

Unigene: 286668 Mouse

实验流程：

全、新、优、品、好四大特点：

瞬时受体电位离子通道蛋白5抗体（M亚家族）规格 全：公司提供上万种产品，涵盖了生物试剂，elisa试剂盒，标准品，培养基，原装耗材，抗体、培养基、ATCC细胞等，基本上各种科研所需产品在我司都能找到。

新：产品更新速度较快，基本上每周都有新产品出现。

优：产品质量好，投诉比较少。

好：我公司具有优质的技术团队，产品一旦售出，实验过程中遇到困难可提供在线技术咨询。使您使用产品时没有任何的后顾之忧。

技术外包服务:

★瞬时受体电位离子通道蛋白5抗体（M亚家族）规格 分子生物学：质粒抽提、PCR、Q-PCR、RT-PCR、分子生物学：基因合成、引物合成、基因测序、载体构建等

★蛋白工程：原核、哺乳动物蛋白表达系统等

★病毒包装：腺病毒、慢病毒等

★抗体工程：磁珠分选、病理染色、WB、ELISA、IP、IF、IHC、FACS、Confocal等等

★细胞工程：细胞表型分析(凋亡、增殖、周期、迁移、侵袭、修复、克隆形成)、细胞培养、细胞膜制备、稳定细胞株构建、细胞RNAi技术等等。

正在热销的相关产品：

Anti-TSHR /FITC 荧光素标记促甲状腺素受体抗体IgGMulti-class antibodies规格： 0.2ml

TNF-Alpha(Tumor Necrosis Factor-Alpha) 人坏死因子-α(多肽抗原)Multi-class antibodies规格： 0.5mg

假性因子/性因子抗体 Anti-VWF 0.1ml

Phospho-RPS6 (Ser235+Ser236) 英文名称： 磷酸化S6核糖体蛋白抗体 0.1ml

LPA2 英文名称： 溶血磷脂酸受体蛋白2抗体 0.2ml

Rhesus antibody Rh phospho-IKK beta(Ser740) 磷酸化KB抑制蛋白激酶β抗体 规格 0.1ml

TNF-Alpha(Tumor Necrosis Factor-Alpha) 人坏死因子-α(多肽抗原)Multi-class antibodies规格： 0.5mg

A/H1N1-M2 Swine(Avian influenza Matrix Protein-2 Swine) A型猪病毒H1N1-M2蛋白Multi-class antibodies规格： 0.5mg

SERPINF2 SerpinF2 鼠单抗 (FITC) Human

Rhesus antibody Rh phospho-CREB-1(Ser121) 磷酸化CREB-1抗体 规格 0.1ml

流式用破膜剂 50T Invitrogen原装

ZIC3 英文名称： 内脏异位相关蛋白/锌指蛋白203抗体 0.2ml

DUSP6 英文名称： 双特异性蛋酸酶6/原活化蛋白激酶磷酸酶3抗体 0.2ml

SERPINF2 SerpinF2 鼠单抗 (FITC) Human

LIF ELISA Kit 大鼠抑制因子Multi-class antibodies规格： 48T

Anti-AIMP2/JTV1/FITC 荧光素标记抗AIMP2抗体IgGMulti-class antibodies规格： 0.2ml

Rhesus antibody Rh FBXL3 FBXL3蛋白抗体 规格 0.2ml

UK ELISA Kit 大鼠尿激酶 96T

BBS6 英文名称： 巴德-毕德氏综合征蛋白BBS6抗体 0.2ml

A4GNT 英文名称： α1,4-N-乙酰葡糖胺转移酶α4Gn-T抗体 0.2ml

Anti-AIMP2/JTV1/FITC 荧光素标记抗AIMP2抗体IgGMulti-class antibodies规格： 0.2ml

人本周蛋白(BJP) ELISA 试剂盒 96T/48T 试剂盒 组装/原装

兔子脂蛋脂酶A2(Lp-PLA2)免疫试剂盒 Rabbit lipoprotein-associated phospholipase A2,Lp-PLA2 ELISA Kit

水通道蛋白4抗体(AQP-4 Ab)ELISA试剂盒 ，英文名： AQP-4 Ab ELISA Kit

Pla25-DihydroxyvitaminD3,HVD3ELISA试剂盒植物25羟基维生素D3(25(OH)D3/25HVD3)ELISA试剂盒规格：96T/48T

GuineapigIerleukin-12,IL-12/P70ELISA试剂盒豚鼠白介素12(IL-12/P70)ELISA试剂盒规格：96T/48T

Humanai-EndomysialAibodyIgA,EMAIgAELISAKit人抗肌内膜抗体IgA(EMAIgA)ELISA试剂盒规格：96T/48T

大鼠糖原合成酶激酶(GSK)ELISA试剂盒 ，英文名： GSK ELISA Kit

人热休克蛋白90(HSP-90)ELISA检测试剂盒HumanHeatShockProtein90,HSP-90ELISAKit 96T/48T

骆驼β内啡肽(β-EP)免疫试剂盒 Camel Beta-Endorphin,β-EP ELISA Kit

CLIAKitforPSAELISAKit大鼠特异性抗原规格：48T/96T

石蜡切片组织BAD蛋白表达荧光显微镜检测试剂盒10/20次

ELISAKitHGF人肝细胞生长因子规格：48T/96T

瞬时受体电位离子通道蛋白5抗体（M亚家族）规格 大鼠细胞周期素D1(Cyclin-D1)ELISA 试剂盒 96T/48T 试剂盒 组装/原装

人胃动蛋白2(GKN2)免疫试剂盒 Human GKN2 ELISA Kit

磷酸烯醇式酸羧化酶(PEPC)测试盒 紫外分光光度法 50管/48样

Ratplateletfactor3,PF3ELISA试剂盒大鼠血小板因子3(PF-3)ELISA试剂盒规格：96T/48T

humanInsulieceptorsubsate2,IRS-2ELISA试剂盒人受体底物2(IRS-2)ELISA试剂盒规格：96T/48T

HumanmembraneIgD,mIgDELISAKit人表面膜免疫球蛋白D(mIgD)ELISA试剂盒规格：96T/48T