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味觉受体蛋白家族2亚基60抗体品牌 英文名称  Anti-T2R60

中文名称  味觉受体蛋白家族2亚基60抗体品牌 

别    名 T2R56; TAS2R60; Taste receptor type 2 member 60; T2R60_HUMAN.

产品属性：

浓    度  1mg/1ml

规 格  0.2ml/200μg

抗体来源  Rabbit

克隆类型   polyclonal

交叉反应   Human

产品类型   一抗  

研究领域    细胞生物 神经生物学 信号转导 细胞膜受体 G蛋白偶联受体 G蛋白信号

蛋白分子量  predicted molecular weight: 36kDa 

性    状   Lyophilized or Liquid

免 疫 原  KLH conjugated synthetic peptide derived from human T2R60

亚    型  IgG

纯化方法   affinity purified by Protein A

储 存 液   Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

味觉受体蛋白家族2亚基60抗体品牌 产品应用   WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 ICC=1:100-500 IF=1:100-500

（石蜡切片需做抗原修复） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品介绍 T2R60 is a 318 amino acid multi-pass membrane protein that belongs to the G-protein coupled receptor T2R family. T2R60 acts as a receptor that may play a role in the perception of bitterness, and is also thought to be involved in sensing the chemical composition of gastrointestinal content. As a gustducin-linked receptor, the activity of T2R60 may stimulate G alpha (alpha gustducin), mediate PLC beta 2 activation and lead to the gating of TRPM5. While expressed in subsets of taste receptor cells of the tongue and palate epithelium, T2R60 is found exclusively in gustducin-positive cells. The gene that encodes T2R60 contains 957 bases and maps to human chromosome 7q35. Chromosome 7 houses over 1,000 genes, comprises nearly 5% of the human genome and has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.

Function : T2R60 may play a role in the perception of bitterness and is gustducin-linked. It is expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells.

Subcellular Location : Cell Membrane; Multi-pass membrane protein.

Tissue Specificity : Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells.

Similarity : Belongs to the G-protein coupled receptor T2R family.

Database links : UniProtKB/Swiss-Prot: P59551.1

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