中文名称  甲状腺受体相关蛋白220抗体说明书 

英文名称  Anti-TRAP220/MED1

别    名 CRSP1; CRSP200; DRIP205; DRIP230; MED1; MED1_HUMAN; Mediator complex subunit 1; Mediator of RNA polymerase II transcription subunit 1; p53 regulatory protein RB18A; PBP; Peroxisome proliferator-activated receptor-binding protein; PPAR binding protein; PPAR-binding protein; PPARBP; PPARGBP; RB18A; Thyroid hormone receptor-associated protein complex 220 kDa component; Thyroid receptor-interacting protein 2; TR-interacting protein 2; TRAP220; TRIP-2; TRIP2; Vitamin D receptor-interacting protein complex component DRIP205; Activator-recruited cofactor 205 kDa component; ARC205.

产品属性：

甲状腺受体相关蛋白220抗体说明书 浓    度  1mg/1ml

规 格  0.2ml/200μg

抗体来源  Rabbit

克隆类型   polyclonal

交叉反应   Human, Mouse, Rat, Pig, Cow, Rabbit

产品类型   一抗  

研究领域     细胞生物 免疫学 染色质和核信号 信号转导 转录调节因子

蛋白分子量  predicted molecular weight: 168kDa 

性    状   Lyophilized or Liquid

免 疫 原  KLH conjugated synthetic peptide derived from human TRAP220/MED1

亚    型  IgG

纯化方法   affinity purified by Protein A

储 存 液   0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide

甲状腺受体相关蛋白220抗体说明书 产品应用   WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500

（石蜡切片需做抗原修复） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品介绍 Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

Function : Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

Subcellular Location : Nucleus. A subset of the protein may enter the nucleolus subsequent to phosphorylation by MAPK1 or MAPK3.

Tissue Specificity : Ubiquitously expressed.

Post-translational modifications : Phosphorylated by MAPK1 or MAPK3 during G2/M phase which may enhance protein stability and promote entry into the nucleolus. Phosphorylated upon DNA damage, probably by ATM or ATR.

Similarity : Belongs to the Mediator complex subunit 1 family.

Database links : UniProtKB/Swiss-Prot: Q15648.4

实验流程：

全、新、优、品、好四大特点：

甲状腺受体相关蛋白220抗体说明书 全：公司提供上万种产品，涵盖了生物试剂，elisa试剂盒，标准品，培养基，原装耗材，抗体、培养基、ATCC细胞等，基本上各种科研所需产品在我司都能找到。

新：产品更新速度较快，基本上每周都有新产品出现。

优：产品质量好，投诉比较少。

好：我公司具有优质的技术团队，产品一旦售出，实验过程中遇到困难可提供在线技术咨询。使您使用产品时没有任何的后顾之忧。

技术外包服务:

★甲状腺受体相关蛋白220抗体说明书 分子生物学：质粒抽提、PCR、Q-PCR、RT-PCR、分子生物学：基因合成、引物合成、基因测序、载体构建等

★蛋白工程：原核、哺乳动物蛋白表达系统等

★病毒包装：腺病毒、慢病毒等

★抗体工程：磁珠分选、病理染色、WB、ELISA、IP、IF、IHC、FACS、Confocal等等

★细胞工程：细胞表型分析(凋亡、增殖、周期、迁移、侵袭、修复、克隆形成)、细胞培养、细胞膜制备、稳定细胞株构建、细胞RNAi技术等等。

正在热销的相关产品：

Anti-TLR9/CD289/FITC 荧光素标记Toll样受体9抗体IgGMulti-class antibodies规格： 0.2ml

BECN1(Beclin1) 一种基因(多肽)Multi-class antibodies规格： 0.5mg

转移生长因子–β3抗体 Anti-TGF-β3 0.1ml

SRXN1 英文名称： 硫氧还蛋白1抗体 0.2ml

ErbB 2 英文名称： HER2受体抗体 0.1ml

Rhesus antibody Rh Phospho-LATS1 (Thr1079) 磷酸化抑制基因LATS1抗体 规格 0.1ml

BECN1(Beclin1) 一种基因(多肽)Multi-class antibodies规格： 0.5mg

Anti-RELN(Reelin)/FITC 荧光素标记络丝蛋白抗体IgGMulti-class antibodies规格： 0.2ml

MBP (Myelin Basic Protein, Rat)peptide 髓鞘碱性蛋白(多肽)大鼠Multi-class antibodies规格： 0.5mg

毒蕈碱型乙酰胆碱受体M1抗体 Anti-ChRM1 0.1ml

SDHB 英文名称： 铬细胞瘤患者基因SDHB抗体 0.1ml

FAM98B 英文名称： FAM98B蛋白抗体 0.2ml

Rhesus antibody Rh phospho-PKC beta 1/2(Thr500) 磷酸化蛋白激酶C β1/β2(Thr500)抗体 规格 0.1ml

MBP (Myelin Basic Protein, Rat)peptide 髓鞘碱性蛋白(多肽)大鼠Multi-class antibodies规格： 0.5mg

MAP-2(microtubule associated protein 2) 微管相关蛋白2抗原Multi-class antibodies规格： 0.5mg

Anti-BRN3A 转录因子Brn3蛋白抗体Multi-class antibodies规格： 0.2ml

Rhesus antibody Rh Pectinesterase 果胶酶抗体 规格 1ml

CD41 浓缩液 0.1ml 进口分装

TSHR 英文名称： 促甲状腺素受体抗体 0.1ml

CK20 英文名称： 细胞角蛋白20抗体 0.1ml

Anti-BRN3A 转录因子Brn3蛋白抗体Multi-class antibodies规格： 0.2ml

TNFSF9 Protein Mouse 重组小鼠 4-1BBL / CD137L / TNFSF9 蛋白 (His 标签)

HeLa 229 人细胞

TNFRSF4 Others Mouse 小鼠 TNFRSF4 / OX40 / CD134 人细胞裂解液 (阳性对照)

EA.hy926人脐细胞融合细胞 EA.hy926 human umbilical vein cell fusion cells DMEM培养基+10%FBS

人羊膜细胞;WISH

大鼠条纹神经元(RNs)(1×106) C6, 大鼠脑细胞 Rattus

CL-0395NCI-H2227(人小细胞细胞)5×106cells/瓶×2

CADM3 Others Rat 大鼠 CADM3 / NECL1 / IGSF4B 人细胞裂解液 (阳性对照)

小鼠肺平滑肌细胞完全培养基 100mL

NIH/3T3小鼠胚胎细胞 NIH/3T3 mouse embryo cells DMEM+10% FBS

IL36B Protein Human 重组人 IL36B / IL1F8 蛋白 (His 标签)

NCI-H2170(人肺鳞癌细胞) 5×106cells/瓶×2 HT-29(细胞)

甲状腺受体相关蛋白220抗体说明书 TNFSF9 Protein Mouse 重组小鼠 4-1BBL / CD137L / TNFSF9 蛋白 (His 标签)

HeLa 229 人细胞

TNFRSF4 Others Mouse 小鼠 TNFRSF4 / OX40 / CD134 人细胞裂解液 (阳性对照)

EA.hy926人脐细胞融合细胞 EA.hy926 human umbilical vein cell fusion cells DMEM培养基+10%FBS

人羊膜细胞;WISH

大鼠条纹神经元(RNs)(1×106) C6, 大鼠脑细胞 Rattus