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瞬时受体电位离子通道蛋白3抗体（M亚家族）说明书 全：公司提供上万种产品，涵盖了生物试剂，elisa试剂盒，标准品，培养基，原装耗材，抗体、培养基、ATCC细胞等，基本上各种科研所需产品在我司都能找到。

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瞬时受体电位离子通道蛋白3抗体（M亚家族）说明书 英文名称  Anti-TRPM3

中文名称  瞬时受体电位离子通道蛋白3抗体（M亚家族）说明书 

别    名 GON 2; GON2; Long transient receptor potential channel 3; LTRPC 3; LTRPC3; Melastatin 2; Melastatin2; MLSN 2; MLSN2; Transient receptor potential cation channel subfamily M member 3; transient receptor potential cation channel, subfamily M, member 3; TRPM 3; TRPM3 protein.

产品属性：

浓    度  1mg/1ml

规 格  0.2ml/200μg

抗体来源  Rabbit

克隆类型   polyclonal

交叉反应   Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep

产品类型   一抗  

研究领域     细胞生物 免疫学 神经生物学 信号转导 通道蛋白

蛋白分子量  predicted molecular weight: 197kDa 

性    状   Lyophilized or Liquid

免 疫 原  KLH conjugated synthetic peptide derived from human TRPM3

亚    型  IgG

纯化方法   affinity purified by Protein A

储 存 液   Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

瞬时受体电位离子通道蛋白3抗体（M亚家族）说明书 产品应用   WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200

（石蜡切片需做抗原修复） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品介绍 The product of this gene belongs to the family of transient receptor potential (TRP) channels. TRP channels are cation-selective channels important for cellular calcium signaling and homeostasis. The protein encoded by this gene mediates calcium entry, and this entry is potentiated by calcium store depletion. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].

Function : Calcium channel mediating constitutive calcium ion entry. Its activity is increased by reduction in extracellular osmolarity, by store depletion and muscarinic receptor activation.

Subcellular Location : Membrane; Multi-pass membrane protein.

Tissue Specificity : Expressed primarily in the kidney and, at lower levels, in brain, testis, ovary, pancreas and spinal cord. Expression in the brain and kidney was determined at protein level. In the kidney, expressed predominantly in the collecting tubular epithelium in the medulla, medullary rays, and periglomerular regions; in the brain, highest levels are found in the cerebellum, choroid plexus, the locus coeruleus, the posterior thalamus and the substantia nigra. Down-regulated in renal tumors compared to normal kidney.

Similarity : Belongs to the transient receptor (TC 1.A.4) family. LTrpC subfamily. TRPM3 sub-subfamily.

Database links :

Entrez Gene: 476326 Dog

Entrez Gene: 80036 Human

Entrez Gene: 226025 Mouse

Entrez Gene: 309407 Rat

Omim: 608961 Human

SwissProt: Q9HCF6 Human

SwissProt: Q5F4S6 Mouse

Unigene: 47288 Human

实验流程：

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