全、新、优、品、好四大特点：

SEL1L抗体品牌 全：公司提供上万种产品，涵盖了生物试剂，elisa试剂盒，标准品，培养基，原装耗材，抗体、培养基、ATCC细胞等，基本上各种科研所需产品在我司都能找到。

新：产品更新速度较快，基本上每周都有新产品出现。

优：产品质量好，投诉比较少。

好：我公司具有优质的技术团队，产品一旦售出，实验过程中遇到困难可提供在线技术咨询。使您使用产品时没有任何的后顾之忧。

SEL1L抗体品牌 英文名称  Anti-SEL1L

中文名称  SEL1L抗体品牌 

别    名 IBD2; PRO1063; Protein sel-1 homolog 1; SE1L1_HUMAN; Sel 1 like protein; Sel 1 suppressor of lin 12 like; Sel-1L; SEL1 LIKE; Sel1l; SEL1LIKE; Suppressor of lin-12-like protein 1; TSA305; UNQ128; UNQ128/PRO1063.

产品属性：

浓    度  1mg/1ml

规 格  0.1ml/100μg 0.2ml/200μg

抗体来源  Rabbit

克隆类型   polyclonal

交叉反应   Human, Mouse, Rat, Pig, Cow, Rabbit

产品类型   一抗  

研究领域     免疫学 信号转导

蛋白分子量  predicted molecular weight: 86kDa 

性    状   Lyophilized or Liquid

免 疫 原  KLH conjugated synthetic peptide derived from human SEL1L

亚    型  IgG

纯化方法   affinity purified by Protein A

储 存 液   0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide

SEL1L抗体品牌 产品应用   WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500

（石蜡切片需做抗原修复） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品介绍 SEL1L, highly similar to the C elegans sel-1 gene, is a recently cloned human gene whose function is under investigation. SEL1L is differentially expressed in tumors and normal tissues and seems to play a role in tumor growth and aggressiveness. It may be an important negative regulator of the "notch" pathway which acts as a key regulator of the cellular proliferation and specification processes in both vertebrates and invertebrates. SEL1L may function in the protein degradation processes through the ubiquitin-proteosome system and perhaps in regulating important pathways such TGF-beta.

It is ubiquitously expressed only in fetal and neoplastic tissues. In normal adult tissues is highly expressed in the acini and in the alpha cells of the pancreas; in general it is highly represented in secretory cells such as plasma cells.

Function : May play a role in Notch signaling (By similarity). May be involved in the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins.

Subunit : Part of a complex containing SEL1L, SYVN1 and DERL2. May form a complex with ERLEC1, HSPA5, OS9, and SYVN1. Interacts with FOXRED2 and EDEM1.

Subcellular Location : Endoplasmic reticulum membrane; Single-pass type I membrane protein.

Tissue Specificity : Highly expressed in pancreas.

Post-translational modifications : N-glycosylated.

Similarity : Belongs to the sel-1 family.

Contains 1 fibronectin type-II domain.

Contains 11 Sel1-like repeats.

Database links : UniProtKB/Swiss-Prot: Q9UBV2.3

实验流程：

正在热销的相关产品：

Anti-VEGF-A/FITC 荧光素标记内皮生长因子A抗体IgGMulti-class antibodies规格： 0.2ml

CD80/B7-1 刺激分子B7-1蛋白抗原Multi-class antibodies规格： 0.5mg

CD34抗体(细胞表面的唾液粘蛋白) Anti-CD34 0.1ml

Somatostatin Receptor 1 英文名称： 生长抑素受体1抗体 0.1ml

ELAC2 英文名称： 遗传性蛋白2抗体 0.2ml

Rhesus antibody Rh Phospho-GRM2/GLUR2 (Tyr869/873/876) 磷酸化促代谢型谷氨酸受体2抗体 规格 0.1ml

CD80/B7-1 刺激分子B7-1蛋白抗原Multi-class antibodies规格： 0.5mg

Anti-TNFAIP3 /FITC 荧光素标记兔抗人、大、小鼠坏死因子α诱导蛋白3抗体IgGMulti-class antibodies规格： 0.2ml

PDGF-R-B 血小板源性生长因子受体-B(抗原)Multi-class antibodies规格： 0.5mg

Toll样受体2抗体 Anti-TLR2 0.1ml

5HT3D + 5HT3E Receptor 英文名称： 5-羟色胺受体3D+3E抗体 0.2ml

EFR3A 英文名称： EFR3A蛋白抗体 0.2ml

Rhesus antibody Rh phospho-KCNC1(Ser503) 磷酸化离子通道蛋白Kv3.1抗体 规格 0.1ml

PDGF-R-B 血小板源性生长因子受体-B(抗原)Multi-class antibodies规格： 0.5mg

RASSF1A(Ras association domain family 1A) Ras相关区域家族1A抗原Multi-class antibodies规格： 0.5mg

Anti-Bax Bax抗体Multi-class antibodies规格： 0.1ml

Rhesus antibody Rh phospho C-Met/HGFR(Tyr1365) 磷酸化原癌基因c-Met抗体 规格 0.1ml

Keratin13 浓缩液 0.1ml 进口分装

UFC1 英文名称： 泛素结合酶UFC1抗体 0.2ml

Chp2 英文名称： 钙调磷酸酶B相关蛋白2抗体 0.1ml

Anti-Bax Bax抗体Multi-class antibodies规格： 0.1ml

IL12A & IL12B Protein Mouse 重组小鼠 IL-12 (IL12A & IL12B Heterodimer) 蛋白

小鼠肾成纤维细胞完全培养基 100mL

HA Others H9N2 甲型 H9N2 (A/Chicken/Hong Kong/G9/97) 血凝素HA1 (Hemagglutinin) 人细胞裂解液 (阳性对照)

P3/NSI/1-Ag4-1 [NS-1]小鼠细胞 P3/NSI/1-Ag4-1 mouse myeloma cell line [NS-1] DMEM培养基+10%FBS

CM-R116大鼠视网膜色素上皮细胞完全培养基100mL

UACC-812(人导管瘤细胞) 5×106cells/瓶×2 EB-3 [EB3](人淋巴样Butt细胞)

CM-M015小鼠胰岛细胞完全培养基100mL

IFNA2 Others Mouse 小鼠 IFNA2 / Ierferon alpha 2 人细胞裂解液 (阳性对照)

小鼠膀胱成纤维细胞完全培养基 100mL

AtT-20小鼠细胞 AtT-20 mouse pituitary tumor cell RPMI-1640(GIBCO)+10%FBS

IL12B Protein Mouse 重组小鼠 IL12B / IL-12B 蛋白 (Fc 标签)

U-118 MG(人脑星形胶质母细胞瘤) 5×106cells/瓶×2 SK-OV-3 [SKOV-3](人细胞)

SEL1L抗体品牌 IL12A & IL12B Protein Mouse 重组小鼠 IL-12 (IL12A & IL12B Heterodimer) 蛋白

小鼠肾成纤维细胞完全培养基 100mL

HA Others H9N2 甲型 H9N2 (A/Chicken/Hong Kong/G9/97) 血凝素HA1 (Hemagglutinin) 人细胞裂解液 (阳性对照)

P3/NSI/1-Ag4-1 [NS-1]小鼠细胞 P3/NSI/1-Ag4-1 mouse myeloma cell line [NS-1] DMEM培养基+10%FBS

CM-R116大鼠视网膜色素上皮细胞完全培养基100mL

UACC-812(人导管瘤细胞) 5×106cells/瓶×2 EB-3 [EB3](人淋巴样Butt细胞)

技术外包服务:

★SEL1L抗体品牌 分子生物学：质粒抽提、PCR、Q-PCR、RT-PCR、分子生物学：基因合成、引物合成、基因测序、载体构建等

★蛋白工程：原核、哺乳动物蛋白表达系统等

★病毒包装：腺病毒、慢病毒等

★抗体工程：磁珠分选、病理染色、WB、ELISA、IP、IF、IHC、FACS、Confocal等等

★细胞工程：细胞表型分析(凋亡、增殖、周期、迁移、侵袭、修复、克隆形成)、细胞培养、细胞膜制备、稳定细胞株构建、细胞RNAi技术等等。