全、新、优、品、好四大特点：

细胞分化蛋白SEPT11抗体规格 全：公司提供上万种产品，涵盖了生物试剂，elisa试剂盒，标准品，培养基，原装耗材，抗体、培养基、ATCC细胞等，基本上各种科研所需产品在我司都能找到。

新：产品更新速度较快，基本上每周都有新产品出现。

优：产品质量好，投诉比较少。

好：我公司具有优质的技术团队，产品一旦售出，实验过程中遇到困难可提供在线技术咨询。使您使用产品时没有任何的后顾之忧。

细胞分化蛋白SEPT11抗体规格 英文名称  Anti-Septin 11

中文名称  细胞分化蛋白SEPT11抗体规格 

别    名 SEP11_HUMAN; SEPT 11; Sept11; Septin-11; Septin11.

产品属性：

浓    度  1mg/1ml

规 格  0.2ml/200μg

抗体来源  Rabbit

克隆类型   polyclonal

交叉反应   Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, Guinea Pig

产品类型   一抗  

研究领域    细胞生物 发育生物学 神经生物学 细胞凋亡 细胞分化 细胞骨架

蛋白分子量  predicted molecular weight: 49kDa 

性    状   Lyophilized or Liquid

免 疫 原  KLH conjugated synthetic peptide derived from human Septin 11

亚    型  IgG

纯化方法   affinity purified by Protein A

储 存 液   Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

细胞分化蛋白SEPT11抗体规格 产品应用   WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500

（石蜡切片需做抗原修复） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品介绍 Septins are members of a conserved family of cytoskeletal GTPases, specifically belonging to the large superclass of P loop GTPases. Septin proteins form homo- and hetero-oligomeric polymers that accumulate into higher-order filaments which may function as dynamic protein scaffolds. Septins play an important role in vesicle trafficking, apoptosis, cytoskeleton remodeling, infection, neurodegeneration, neoplasia and cytokinesis. Septin 11 is mainly present in brain tissue. It has been found to dominantly co-localize with microtubules and Actin stress fibers in HMEC cells and REF52 cells, and to partially co-localize with microtubules and stress fibers in HeLa cells. SEPT11 (the gene encoding Septin 11) is confined to the same tissues as those that express SEPT5, suggesting that SEPT11 and SEPT5 are components of a cell-specific septin complex.

Function : Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential). May play a role in the cytoarchitecture of neurons, including dendritic arborization and dendritic spines, and in GABAergic synaptic connectivity (By similarity). During Listeria monocytogenes infection, not required for the bacterial entry process, but restricts its efficacy.

Subunit : Septins polymerize into heterooligomeric protein complexes that form filaments, and can associate with cellular membranes, actin filaments and microtubules. GTPase activity is required for filament formation. Interacts with SEPT7, SEPT9 and SEPT12. Forms homooligomers.

Subcellular Location : Cytoplasm, cytoskeleton. Cell junction, synapse. Cell projection, dendritic spine. Cell projection, axon (By similarity). Note=Partly colocalizes with stress fibers and microtubules. During bacterial infection, displays a collar shape structure next to actin at the pole of invading bacteria.

Tissue Specificity : Widely expressed, except in leukocytes.

DISEASE : Note=A chromosomal aberration involving SEPT11 may be a cause of chronic neutrophilic leukemia. Translocation t(4;11)(q21;q23) with MLL/HRX.

Similarity : Belongs to the septin family.

Database links : UniProtKB/Swiss-Prot: Q9NVA2.3

实验流程：

正在热销的相关产品：

Anti-Stra8/FITC 荧光素标记视黄酸激活基因8抗体IgGMulti-class antibodies规格： 0.2ml

G Protein(Guanine nucleotide-binding regulatory protein) G蛋白(鸟苷酸结合蛋白)(抗原)Multi-class antibodies规格： 0.5mg

“蒙”蛋白又称“波克曼”蛋白抗体 Anti-Pokemon 0.2ml

SCP3 英文名称： 联会复合体蛋白3抗体 0.1ml

EGF 英文名称： 抗表皮生长因子抗体 0.1ml

Rhesus antibody Rh Phospho-Mst1(Thr183)/Mst2(Thr180) 磷酸化蛋白激酶MST抗体 规格 0.1ml

G Protein(Guanine nucleotide-binding regulatory protein) G蛋白(鸟苷酸结合蛋白)(抗原)Multi-class antibodies规格： 0.5mg

Anti-PHD3 /FITC 荧光素标记脯氨酸羟化酶抗体IgGMulti-class antibodies规格： 0.2ml

Rabbit Anti-Avidin/Gold 金标记兔抗亲和素 (10nm/15nm)Multi-class antibodies规格： 2ml

FasL抗体 Anti-FasLAnti-FasL 0.1ml

Goat Anti-rabbit IgG/Gold 胶体金标记的羊抗兔IgG 0.5ml

Factor XII light chain 英文名称： 凝血因子12轻链抗体 0.2ml

Rhesus antibody Rh phospho-Syndecan 4(Ser179) 磷酸化多配体聚糖4(Ser179)抗体 规格 0.1ml

Rabbit Anti-Avidin/Gold 金标记兔抗亲和素 (10nm/15nm)Multi-class antibodies规格： 2ml

NR1/NMDAR1(N-Methyl-d-Asprtate receptor 1) 谷氨酸受体1抗原Multi-class antibodies规格： 0.5mg

Anti-AKR1B1 醛糖还原酶抗体Multi-class antibodies规格： 0.2ml

Rhesus antibody Rh phospho-ATF4/CREB-2(Ser245) 磷酸化活化转录因子4抗体 规格 0.1ml

山羊SP(HRP)试剂盒 140片 进口原料

UROD 英文名称： 尿卟啉原脱羧酶抗体 0.2ml

DICER1 英文名称： 核糖核酸酶Dicer抗体 0.1ml

Anti-AKR1B1 醛糖还原酶抗体Multi-class antibodies规格： 0.2ml

LIF Protein Human 重组人 LIF 蛋白 (Fc 标签)

小鼠肠内皮细胞完全培养基 100mL

CD8B Others Human 人 CD8B / P37 / LEU2 人细胞裂解液 (阳性对照)

marc-145猴胚胎肾上皮细胞 Marc-145 monkey embryonic kidney epithelial cells DMEM+10% FBS

CL-0167NCI-H292(人细胞)5×106cells/瓶×2

RK1(大鼠肾细胞) 5×106cells/瓶×2 786-0(肾透明细胞腺癌)

CM-M118小鼠虹膜色素上皮细胞完全培养基100mL

IL3RA Others Canine 狗 IL3RA 人细胞裂解液 (阳性对照)

间充质干细胞培养基MSCM-sf-prf

SW480[SW-480]细胞，人细胞 人胚肾上皮包装细胞,GP2-293Luc细胞 原代上皮细胞培养特制添加剂Many types of cells包装：5/2.5/1ml

山羊皮肤成纤维样细胞;DG-S1

RBP4 Others Human 人 RBP4 人细胞裂解液 (阳性对照)

细胞分化蛋白SEPT11抗体规格 LIF Protein Human 重组人 LIF 蛋白 (Fc 标签)

小鼠肠内皮细胞完全培养基 100mL

CD8B Others Human 人 CD8B / P37 / LEU2 人细胞裂解液 (阳性对照)

marc-145猴胚胎肾上皮细胞 Marc-145 monkey embryonic kidney epithelial cells DMEM+10% FBS

CL-0167NCI-H292(人细胞)5×106cells/瓶×2

RK1(大鼠肾细胞) 5×106cells/瓶×2 786-0(肾透明细胞腺癌)

技术外包服务:

★细胞分化蛋白SEPT11抗体规格 分子生物学：质粒抽提、PCR、Q-PCR、RT-PCR、分子生物学：基因合成、引物合成、基因测序、载体构建等

★蛋白工程：原核、哺乳动物蛋白表达系统等

★病毒包装：腺病毒、慢病毒等

★抗体工程：磁珠分选、病理染色、WB、ELISA、IP、IF、IHC、FACS、Confocal等等

★细胞工程：细胞表型分析(凋亡、增殖、周期、迁移、侵袭、修复、克隆形成)、细胞培养、细胞膜制备、稳定细胞株构建、细胞RNAi技术等等。