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产品展厅
丝氨酸/苏氨酸蛋白激酶SRPK7抗体费用
  • 品牌:上海莼试
  • 产地:进口、国产
  • 货号:CS11341
  • 发布日期: 2019-01-14
  • 更新日期: 2024-11-26
产品详请
产地 进口、国产
品牌 上海莼试
保存条件 Store at -20 °C
货号 CS11341
应用范围 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
CAS编号
抗体名 Anti-SFRS7/9G8/SRp20
克隆性
靶点 详见说明书
适应物种 详见说明书
形态 详见说明书
宿主 详见说明书
亚型 IgG
标识物 详见说明书
浓度 1mg/1ml%
免疫原 KLH conjugated synthetic peptide derived from human SRp20 (2-70aa)

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丝氨酸/苏氨酸蛋白激酶SRPK7抗体费用 全:公司提供上万种产品,涵盖了生物试剂,elisa试剂盒,标准品,培养基,原装耗材,抗体、培养基、ATCC细胞等,基本上各种科研所需产品在我司都能找到。

新:产品更新速度较快,基本上每周都有新产品出现。

优:产品质量好,投诉比较少。

好:我公司具有优质的技术团队,产品一旦售出,实验过程中遇到困难可提供在线技术咨询。使您使用产品时没有任何的后顾之忧。

丝氨酸/苏氨酸蛋白激酶SRPK7抗体费用 英文名称  Anti-SFRS7/9G8/SRp20

中文名称  丝氨酸/苏氨酸蛋白激酶SRPK7抗体费用 

     9G8; AAG3; HSSG1; RBM37; Splicing factor 9G8; Splicing factor, arginine/serine rich 7; ZCCHC20; ZCRB2; SRSF7_HUMAN.

产品属性:

      1mg/1ml

  0.2ml/200μg

抗体来源  Rabbit

克隆类型   polyclonal

交叉反应   Human, Mouse, Rat, Chicken, Cow, Zebrafish

产品类型   一抗  

研究领域    细胞生物 神经生物学 信号转导 表观遗传学

蛋白分子量  predicted molecular weight: 27kDa 

       Lyophilized or Liquid

  KLH conjugated synthetic peptide derived from human SRp20 (2-70aa)

      IgG

纯化方法   affinity purified by Protein A

   Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

丝氨酸/苏氨酸蛋白激酶SRPK7抗体费用 产品应用   WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500

(石蜡切片需做抗原修复) 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品介绍 Pre-mRNA splicing enhancer elements are short RNA sequences capable of activating weak splice sites in nearby introns, and they are required for accurate splice site recognition and the control of alternative splicing (1). Splicing enhancer elements contain specific binding sites for serine/arginine (SR)-rich splicing factors, which include SC35, 9G8, SRp20, and SF2/ASF (2). The family of SR factors all contain one or more RNA recognition motifs (RRM) and an arginine/serine (RS)-rich domain, and they are essential for constitutive splicing and also regulate splicing in a concentration-dependent manner by influencing the selection of alternative splice sites (3,4). The majority of SR proteins, including SC35 and SRp40, are confined to the nucleus, while SF2/ASF, SRp20, and 9G8 are continuously shuttled between the nucleus and the cytoplasm and contribute to mRNA transport (5). The activity of SR proteins in regulated splicing is antagonized by members of the hnRNP A/B family of proteins, which induce drastic shifts in the selection of splicing-sites (6).

Function : Splicing factor, arginine/serine rich 7 is required for pre mRNA splicing. Can also modulate alternative splicing in vitro.

Subunit : Found in large molecular weight complexes containingCCNL1 and the p110 isoforms of either CDC2L1 or CDC2L2. Interactswith CCNL2 and CPSF6.

Subcellular Location : Nuclear

Tissue Specificity : Brain, liver, kidney and lung.

Post-translational modifications : Extensively phosphorylated on serine residues in the RSdomain.

Similarity : Belongs to the splicing factor SR family.

Contains 1 CCHC-type zinc finger.

Contains 1 RRM (RNA recognition motif) domain.

Database links : UniProtKB/Swiss-Prot: Q16629.1

实验流程:

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技术外包服务:

丝氨酸/苏氨酸蛋白激酶SRPK7抗体费用 分子生物学:质粒抽提、PCRQ-PCRRT-PCR、分子生物学:基因合成、引物合成、基因测序、载体构建等

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