环指蛋白13抗体说明书 英文名称  Anti-RNF13

中文名称  环指蛋白13抗体说明书 

别    名 E3 ubiquitin-protein ligase RNF13; FLJ93817; MGC13689; RING finger protein 13; Ring zinc finger protein; RNF 13; Rnf13; RNF13_HUMAN; RZF.

产品属性：

浓    度  1mg/1ml

规 格  0.2ml/200μg

抗体来源  Rabbit

克隆类型   polyclonal

交叉反应   Human, Mouse, Rat, Cow, Horse, Rabbit, Sheep

产品类型   一抗  

研究领域    细胞生物 免疫学 信号转导

蛋白分子量  predicted molecular weight: 39kDa 

性    状   Lyophilized or Liquid

免 疫 原  KLH conjugated synthetic peptide derived from human RNF13

亚    型  IgG

纯化方法   affinity purified by Protein A

储 存 液   Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

环指蛋白13抗体说明书 产品应用   WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200

（石蜡切片需做抗原修复） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品介绍 The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. RNF13 (ring finger protein 13), also known as RZF, FLJ93817 or MGC13689, is a novel 381 amino acid E3 ubiquitin ligase that localizes to the nucleus. RNF13 contains one RING-type zinc finger and the C-terminal portion of RNF13 has the ability to mediate ubiquitination. Recent studies suggest that RNF13 may be involved in the development of pancreatic cancer via ubiquitin-mediated modification of proteins. The gene encoding RNF13 maps to human chromsome 3q25.1, and a pseudogene (which is also located on chromosome 3), exists for this gene.

Function : E3 ubiquitin-protein ligase that may play a role in controlling cell proliferation.

Subcellular Location : Endoplasmic reticulum membrane. Golgi apparatus membrane. Late endosome membrane. Lysosome membrane. Nucleus inner membrane. Under certain conditions, relocalizes to recycling endosomes and to the inner nuclear membrane.

Tissue Specificity : Widely expressed (at protein level). In normal pancreas, expressed in islets, but not in ducts, nor in acini (at protein level).

Post-translational modifications : Auto-ubiquitinated.

Similarity : Contains 1 PA (protease associated) domain.

Contains 1 RING-type zinc finger.

Database links : UniProtKB/Swiss-Prot: O43567.1

实验流程：

全、新、优、品、好四大特点：

环指蛋白13抗体说明书 全：公司提供上万种产品，涵盖了生物试剂，elisa试剂盒，标准品，培养基，原装耗材，抗体、培养基、ATCC细胞等，基本上各种科研所需产品在我司都能找到。

新：产品更新速度较快，基本上每周都有新产品出现。

优：产品质量好，投诉比较少。

好：我公司具有优质的技术团队，产品一旦售出，实验过程中遇到困难可提供在线技术咨询。使您使用产品时没有任何的后顾之忧。

正在热销的相关产品：

human IFN- Alpha (Interferon Alpha ) 干扰素-α抗原(人)Multi-class antibodies规格： 0.5mg

Anti-ACE1 紧张素转换酶ACE1抗体Multi-class antibodies规格： 0.1ml

Rhesus antibody Rh Phospho-CEBP beta (Ser105) 磷酸化转录调节因子CEBP β抗体 规格 0.1ml

兔抗人IgM血清 0.5ml 国产

WRCH-1 英文名称： WRCH1抗体 0.1ml

DRD1 英文名称： 多巴胺受体D1抗体 0.1ml

Anti-ACE1 紧张素转换酶ACE1抗体Multi-class antibodies规格： 0.1ml

Anti-SATB1/FITC 荧光素标记核基质结合区结合蛋白1抗体IgGMulti-class antibodies规格： 0.2ml

rHBcAg 重组乙毒核心抗原Multi-class antibodies规格： 100ug

鼠抗人β2微球蛋白抗体 Anti-β-2-MG 0.1ml

Spindlin 1 英文名称： 相关蛋白抗体 0.1ml

FAK 英文名称： 粘着斑激酶抗体 0.1ml

Rhesus antibody Rh Phospho-PDGFRA(Tyr754) 磷酸化血小板源性生长因子受体-α抗体 规格 0.1ml

rHBcAg 重组乙毒核心抗原Multi-class antibodies规格： 100ug

Synphilin-1 英文名称： 核突触蛋白相互作用蛋白1抗体 0.1ml

Endo G 英文名称： 核酸内切酶G抗体 0.1ml

细胞间粘附分子-3抗体 Anti-CD50/ICAM-3 0.1ml

Anti-p-VEGFR2/FITC 荧光素标记兔抗人、大、小鼠磷酸化内皮生长因子受体2抗体IgGMulti-class antibodies规格： 0.2ml

Rhesus antibody Rh phospho-GIT1(Tyr510) 磷酸化G蛋白偶联受体激酶相互作用蛋白1 规格 0.1ml

Cdkn1c/p57/Kip2 (Cyclindependent kinase inhibitor 1C) 周期蛋白依赖激酶抑制因子1C抗原Multi-class antibodies规格： 0.5mg

TDGF1 Protein Human 重组人 Cripto / TDGF1 蛋白 (His 标签)

MT-4 人急性淋巴母细胞细胞

KLK3 Others Human 人 KLK3 / PSA / Kallikrein-3 人细胞裂解液 (阳性对照)

A-673 人横纹肌瘤细胞 A-673 rhabdomyoma cells DMEM培养基+10%FBS

人癌细胞;MDA-MB-231

人脐内皮细胞;HUV-EC 人*星状细胞完全培养基 100mL

CL-0251MC3T3-E1(小鼠胚胎成骨细胞前体细胞)5×106cells/瓶×2

OLR1 Others Rat 大鼠 OLR1 / LOX1 人细胞裂解液 (阳性对照)

人海马趾神经细胞总RNAHN-h NA

山羊肾上皮样细胞;DG-K1 人胚肾细胞，293T/17[HEK 293T/17]细胞 L7912细胞，615小鼠T细胞性瘤株

双位点HC-kit受体细胞株;DMF7

HA Others H5N1 甲型 H5N1 血凝素HA1 (Hemagglutinin) 人细胞裂解液 (阳性对照)

环指蛋白13抗体说明书 TDGF1 Protein Human 重组人 Cripto / TDGF1 蛋白 (His 标签)

MT-4 人急性淋巴母细胞细胞

KLK3 Others Human 人 KLK3 / PSA / Kallikrein-3 人细胞裂解液 (阳性对照)

A-673 人横纹肌瘤细胞 A-673 rhabdomyoma cells DMEM培养基+10%FBS

人癌细胞;MDA-MB-231

人脐内皮细胞;HUV-EC 人*星状细胞完全培养基 100mL

技术外包服务:

★环指蛋白13抗体说明书 分子生物学：质粒抽提、PCR、Q-PCR、RT-PCR、分子生物学：基因合成、引物合成、基因测序、载体构建等

★蛋白工程：原核、哺乳动物蛋白表达系统等

★病毒包装：腺病毒、慢病毒等

★抗体工程：磁珠分选、病理染色、WB、ELISA、IP、IF、IHC、FACS、Confocal等等

★细胞工程：细胞表型分析(凋亡、增殖、周期、迁移、侵袭、修复、克隆形成)、细胞培养、细胞膜制备、稳定细胞株构建、细胞RNAi技术等等。