产地 | 进口、国产 |
品牌 | 上海莼试 |
保存条件 | Store at -20 °C |
货号 | CS10965 |
应用范围 | WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 |
CAS编号 | |
抗体名 | Anti-RCAN2/DSCR1L1 |
克隆性 | |
靶点 | 详见说明书 |
适应物种 | 详见说明书 |
形态 | 详见说明书 |
宿主 | 详见说明书 |
亚型 | IgG |
标识物 | 详见说明书 |
浓度 | 1mg/1ml% |
免疫原 | KLH conjugated synthetic peptide derived from human RCAN2/DSCR1L1 |
中文名称 钙调神经磷酸酶调节蛋白2抗体(唐氏综合征候选区域蛋白1样蛋白2)费用
英文名称 Anti-RCAN2/DSCR1L1
别 名 Calcipressin 2; Calcipressin-2; CSP2; Down syndrome candidate region 1-like 1; Down syndrome critical region gene 1 like 1 protein; MCIP2; Myocyte enriched calcineurin interacting protein 2; Myocyte-enriched calcineurin-interacting protein 2; RCAN2; RCAN2_HUMAN; RCN2; Regulator of calcineurin 2; Thyroid hormone responsive protein ZAKI4; Thyroid hormone-responsive protein ZAKI-4; ZAKI4.
产品属性:
钙调神经磷酸酶调节蛋白2抗体(唐氏综合征候选区域蛋白1样蛋白2)费用 浓 度 1mg/1ml
规 格 0.1ml/200μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep
产品类型 一抗
研究领域 心 细胞生物 染色质和核信号 神经生物学 信号转导 细胞凋亡 转录调节因子 表观遗传学
蛋白分子量 predicted molecular weight: 22kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human RCAN2/DSCR1L1
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
钙调神经磷酸酶调节蛋白2抗体(唐氏综合征候选区域蛋白1样蛋白2)费用 产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 Calcineurin is a Ca(2+) dependent protein phosphatase that is involed in several neuornal functions. Proteins belonging to the RCAN (Regulator of calcineurin) family modulate the activity of Calcineurin through a valine-rich region within their carboxyl tail. RCANs compete with NFATs (Nuclear factor of activated T-cells) for binding to the same docking site in calcineurin, which results in either inhibition or activation of calcineurin activity. Calcipressin-2, also known as RCAN2 and DSCR1L1 (Down syndrome candidate region 1-like 1), is a 197 amino acid protein that is highly expressed in both the cytoplasm and nucleus of neurons and is the only RCAN family member that is found in glial cells. Calcipressin-3, also known as RCAN3 and DSCR1L2 (Down syndrome candidate region 1-like protein 2), is a 241 amino acid protein that potentially is involved in central nervous system development. Calcipressin-3 interacts with cardiac troponin I, suggesting that it may play a role in cardiac contraction events.
Function : Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development.
Tissue Specificity : Expressed in fibroblasts, heart, brain, liver, and skeletal muscle but not in placenta, lung, kidney and pancreas.
Similarity : Belongs to the RCAN family.
Database links : UniProtKB/Swiss-Prot: Q14206.3
实验流程:
全、新、优、品、好四大特点:
钙调神经磷酸酶调节蛋白2抗体(唐氏综合征候选区域蛋白1样蛋白2)费用 全:公司提供上万种产品,涵盖了生物试剂,elisa试剂盒,标准品,培养基,原装耗材,抗体、培养基、ATCC细胞等,基本上各种科研所需产品在我司都能找到。
新:产品更新速度较快,基本上每周都有新产品出现。
优:产品质量好,投诉比较少。
好:我公司具有优质的技术团队,产品一旦售出,实验过程中遇到困难可提供在线技术咨询。使您使用产品时没有任何的后顾之忧。
技术外包服务:
★钙调神经磷酸酶调节蛋白2抗体(唐氏综合征候选区域蛋白1样蛋白2)费用 分子生物学:质粒抽提、PCR、Q-PCR、RT-PCR、分子生物学:基因合成、引物合成、基因测序、载体构建等
★蛋白工程:原核、哺乳动物蛋白表达系统等
★病毒包装:腺病毒、慢病毒等
★抗体工程:磁珠分选、病理染色、WB、ELISA、IP、IF、IHC、FACS、Confocal等等
★细胞工程:细胞表型分析(凋亡、增殖、周期、迁移、侵袭、修复、克隆形成)、细胞培养、细胞膜制备、稳定细胞株构建、细胞RNAi技术等等。
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